Harvard Center for Bioethics, Harvard Medical School, Boston, MA, USA.
Program on Regulation, Therapeutics, and Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Sci Transl Med. 2020 Apr 22;12(540). doi: 10.1126/scitranslmed.aaw7745.
Precision medicine is beginning to make an impact on the treatment of different diseases, but there are still challenges that must be overcome, such as the complexity of interventions, the need for marker validation, and the level of evidence necessary to demonstrate effectiveness. In this Perspective, we describe how evidence landscapes can help to address these challenges.
精准医学开始对不同疾病的治疗产生影响，但仍存在一些必须克服的挑战，例如干预措施的复杂性、标志物验证的需求以及证明有效性所需的证据水平。在本观点中，我们描述了证据图谱如何帮助解决这些挑战。
