Ross J Megan, Pacheco-Colón Ileana, Hawes Samuel W, Gonzalez Raul
Institute for Behavior Genetics, University of Colorado Boulder, Boulder, Colorado.
Center for Children and Families, Department of Psychology, Florida International University, Miami, Florida.
Cannabis Cannabinoid Res. 2020 Feb 27;5(1):81-88. doi: 10.1089/can.2019.0091. eCollection 2020 Mar 1.
Literature on the association between cannabis use and body mass index (BMI) among adults suggests that greater cannabis use is associated with a lower BMI. However, results are mixed among adolescents, with both cross-sectional and longitudinal studies finding positive, negative, and nonsignificant associations between cannabis use and BMI. This longitudinal study aims to shed light on these associations by prospectively examining the associations between cannabis use and BMI across a 2-year window in a large sample of adolescent cannabis users. Participants were 401 adolescents ages 14-17 at baseline who were at risk for escalation in their use of cannabis. We conducted a parallel process latent growth curve model to examine associations between the cannabis use intercept, BMI intercept, cannabis use slope, and BMI slope. Results showed that baseline BMI predicted a positive and significant association with cannabis use slope. In addition, there was a significant and negative correlation between the cannabis use slope and the BMI slope. These significant associations remained after controlling for relevant covariates. Results are consistent with the adult literature that reports a negative association between cannabis use and BMI. Future research should focus on uncovering the mechanisms that may drive the association between cannabis use and BMI.
关于成年人中使用大麻与体重指数(BMI)之间关联的文献表明,大麻使用量增加与较低的BMI相关。然而,青少年中的研究结果不一,横断面研究和纵向研究均发现大麻使用与BMI之间存在正相关、负相关和无显著关联。这项纵向研究旨在通过前瞻性地考察一大群青少年大麻使用者在两年时间跨度内大麻使用与BMI之间的关联,来阐明这些关系。参与者为401名基线年龄在14至17岁、有大麻使用量增加风险的青少年。我们进行了一个平行过程潜在增长曲线模型,以检验大麻使用截距、BMI截距、大麻使用斜率和BMI斜率之间的关联。结果显示,基线BMI预测了与大麻使用斜率呈正且显著的关联。此外,大麻使用斜率与BMI斜率之间存在显著的负相关。在控制了相关协变量后,这些显著关联依然存在。研究结果与成年人群体的文献一致,即报告了大麻使用与BMI之间存在负相关。未来的研究应专注于揭示可能驱动大麻使用与BMI之间关联的机制。