Preparation and characterization of a reconstituted stratum corneum film as a model membrane for skin transport.
作者信息
Kock W R, Berner B, Burns J L, Bissett D L
机构信息
Procter and Gamble Company, Miami Valley Laboratories, Cincinnati, OH 45239.
出版信息
Arch Dermatol Res. 1988;280(4):252-6. doi: 10.1007/BF00513965.
PMID:3233015
Abstract
A zwitterionic surfactant, 6-eicosyldimethyl ammoniohexanoate (C20AH), completely disaggregates stratum corneum into individual cells. The cells can be cast into a film of reconstituted stratum corneum (RSC). Such films prepared from pig and human skin mimic intact human stratum corneum in microscopic, mechanical, and barrier evaluations. The films are useful as model membranes for skin transport experiments.
摘要
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