基于生物医学级超高分子量聚乙烯石蜡油和碳纳米填料的耐磨纳米复合材料：初步生物相容性和抗菌活性研究。
Wear Resistant Nanocomposites Based on Biomedical Grade UHMWPE Paraffin Oil and Carbon Nano-Filler: Preliminary Biocompatibility and Antibacterial Activity Investigation.
作者信息
Catauro Michelina, Scolaro Cristina, Dal Poggetto Giovanni, Pacifico Severina, Visco Annamaria
机构信息
Department of Engineering, University of Campania "Luigi Vanvitelli", Via Roma 29, I-81031 Aversa, Italy.
Department of Engineering, University of Messina, C.da Di Dio, 98166 Messina, Italy.
出版信息
Polymers (Basel). 2020 Apr 22;12(4):978. doi: 10.3390/polym12040978.
In the present paper, we investigate the effectiveness of nanocomposites (composed of ultra-high molecular weight polyethylene (UHMWPE) mixed with carbon nano-filler (CNF) and medical grade paraffin oil (PO), from the biological point of view. Wear measurements were carried out without (air) and with lubricant (distilled water, natural, and artificial lubricant), and antibacterial activity and cytotoxicity were evaluated. The results highlighted that the presence of CNF is important in the nanocomposite formulation because it reduces the wear rate and prevents oxidative degradation during its processing. An amount of 1.0 wt % of CNF is best because it reaches the optimal distribution within the polymeric matrix, resulting in the best wear resistant, bio-active, and anti-bacterial nanocomposite among all investigated samples.
在本论文中，我们从生物学角度研究了纳米复合材料（由超高分子量聚乙烯（UHMWPE）与碳纳米填料（CNF）和医用级石蜡油（PO）组成）的有效性。在无润滑（空气）和有润滑剂（蒸馏水、天然和人工润滑剂）的情况下进行了磨损测量，并评估了抗菌活性和细胞毒性。结果表明，CNF的存在在纳米复合材料配方中很重要，因为它降低了磨损率并防止其加工过程中的氧化降解。1.0 wt%的CNF含量最佳，因为它在聚合物基体中达到了最佳分布，在所有研究样品中形成了耐磨性、生物活性和抗菌性能最佳的纳米复合材料。
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