• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

1 例 HIV 合并低 CD4T 细胞计数的新型冠状病毒肺炎（COVID-19）患者。

One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4 T-cell count.

机构信息

Department of Neurosurgery, Changhai Hospital of the Second Military Medical University, Shanghai, China; Wuhan Huo Shen Shan Hospital, Wuhan, China.

Department of Infectious Diseases, Airforce Hospital of Southern Theater Command, Guangzhou, China.

出版信息

Int J Infect Dis. 2020 Jul;96:148-150. doi: 10.1016/j.ijid.2020.04.060. Epub 2020 Apr 23.

DOI:10.1016/j.ijid.2020.04.060
PMID:32335339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7194654/
Abstract

The ongoing outbreak of COVID-19 that began in Wuhan, China, become an emergency of international concern when thousands of people were infected around the world. This study reports a case simultaneously infected by SARS-Cov-2 and HIV, which showed a longer disease course and slower generation of specific antibodies. This case highlights that a co-infection of SARS-Cov-2 and HIV may severely impair the immune system.

摘要

中国武汉爆发的新冠肺炎疫情，在全球范围内有数千人感染，成为国际关注的紧急事件。本研究报告了一例同时感染 SARS-CoV-2 和 HIV 的病例，该病例表现出较长的疾病过程和较慢的特异性抗体产生。该病例强调了 SARS-CoV-2 和 HIV 的合并感染可能严重损害免疫系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/7194654/1a4a2aa41571/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/7194654/1a4a2aa41571/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/7194654/1a4a2aa41571/gr1_lrg.jpg

相似文献

1
One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4 T-cell count.1 例 HIV 合并低 CD4T 细胞计数的新型冠状病毒肺炎（COVID-19）患者。
Int J Infect Dis. 2020 Jul;96:148-150. doi: 10.1016/j.ijid.2020.04.060. Epub 2020 Apr 23.
2
No Significant Effect of COVID-19 on Immunological and Virological Parameters in Patients With HIV-1 Infection.新冠病毒对HIV-1感染患者的免疫学和病毒学参数无显著影响。
J Acquir Immune Defic Syndr. 2020 Sep 1;85(1):e6-e8. doi: 10.1097/QAI.0000000000002427.
3
Editorial - Coronavirus disease 2019 and people living with HIV: clinical considerations.社论 - 2019冠状病毒病与艾滋病毒感染者：临床考量
Eur Rev Med Pharmacol Sci. 2020 Jul;24(13):7534-7539. doi: 10.26355/eurrev_202007_21928.
4
HIV and Human Coronavirus Coinfections: A Historical Perspective.人类免疫缺陷病毒（HIV）与人类冠状病毒合并感染：历史视角。
Viruses. 2020 Aug 26;12(9):937. doi: 10.3390/v12090937.
5
Coinfection With HIV and SARS-CoV-2 in Wuhan, China: A 12-Person Case Series.中国武汉的 HIV 和 SARS-CoV-2 合并感染：12 人病例系列。
J Acquir Immune Defic Syndr. 2020 Sep 1;85(1):1-5. doi: 10.1097/QAI.0000000000002424.
6
Impact of New Coronavirus Epidemics on HIV-Infected Patients.新型冠状病毒疫情对艾滋病毒感染患者的影响。
AIDS Rev. 2020;22(1):57-58. doi: 10.24875/AIDSRev.M20000031.
7
HIV and SARS-CoV-2: points to consider to face this new pandemic.人类免疫缺陷病毒与严重急性呼吸综合征冠状病毒2：应对这一新疫情需考虑的要点。
Medwave. 2020 Oct 27;20(9):e8049. doi: 10.5867/medwave.2020.09.8049.
8
Continuity of HIV Care in the Presence of COVID-19.2019冠状病毒病背景下的艾滋病病毒持续护理
AIDS Rev. 2020;22(3):131-132. doi: 10.24875/AIDSRev.20000074.
9
Concurrent COVID-19 and Pneumocystis jirovecii pneumonia in a severely immunocompromised 25-year-old patient.一名25岁严重免疫功能低下患者同时感染新冠病毒和耶氏肺孢子菌肺炎。
Int J Infect Dis. 2020 Oct;99:119-121. doi: 10.1016/j.ijid.2020.07.061. Epub 2020 Aug 5.
10
SARS-CoV-2 and HIV coinfection: clinical experience from Rhode Island, United States.SARS-CoV-2 和 HIV 合并感染：美国罗德岛的临床经验。
J Int AIDS Soc. 2020 Jul;23(7):e25573. doi: 10.1002/jia2.25573.

引用本文的文献

1
Clinical outcomes and immunological response to SARS-CoV-2 infection among people living with HIV.HIV 感染者感染 SARS-CoV-2 的临床结局和免疫反应。
Exp Biol Med (Maywood). 2024 Apr 2;249:10059. doi: 10.3389/ebm.2024.10059. eCollection 2024.
2
A review of the clinical characteristics and management of immunosuppressed patients living with HIV or solid organ transplants infected with SARS-CoV-2 omicron variants.奥密克戎变异株感染 HIV 或实体器官移植后免疫抑制患者的临床特征和管理综述。
Front Public Health. 2024 Feb 22;12:1327093. doi: 10.3389/fpubh.2024.1327093. eCollection 2024.
3
Respiratory bacterial co-infections and their antibiotic resistance pattern in COVID-19 patients at a tertiary care centre in India.

本文引用的文献

1
Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China.中国武汉 2019 年冠状病毒病（COVID-19）患者免疫反应失调。
Clin Infect Dis. 2020 Jul 28;71(15):762-768. doi: 10.1093/cid/ciaa248.
2
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis.新型冠状病毒感染诊断用快速 IgM-IgG 联合抗体检测试剂的研制与临床应用
J Med Virol. 2020 Sep;92(9):1518-1524. doi: 10.1002/jmv.25727. Epub 2020 Apr 13.
3
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
印度一家三级护理中心的新冠肺炎患者呼吸道细菌合并感染及其抗生素耐药模式
Access Microbiol. 2023 Jun 22;5(6). doi: 10.1099/acmi.0.000514.v3. eCollection 2023.
4
Risk Factors of Clonally Related, Multi, and Extensively Drug-Resistant in Severely Ill COVID-19 Patients.重症 COVID-19 患者中克隆相关、多重及广泛耐药的危险因素
Can J Infect Dis Med Microbiol. 2023 Feb 13;2023:3139270. doi: 10.1155/2023/3139270. eCollection 2023.
5
HIV-Associated Mycobacterium Avium Complex, Oral Candida, and SARS-CoV-2 Co-Infection: A Rare Case Report.人类免疫缺陷病毒相关鸟分枝杆菌复合体、口腔念珠菌与严重急性呼吸综合征冠状病毒2型合并感染：1例罕见病例报告
Infect Drug Resist. 2022 Dec 2;15:7037-7042. doi: 10.2147/IDR.S390333. eCollection 2022.
6
Six-month humoral immune response to inactivated COVID-19 vaccine among people living with HIV.感染 HIV 人群接种新冠灭活疫苗后 6 个月的体液免疫反应。
Front Immunol. 2022 Oct 17;13:988304. doi: 10.3389/fimmu.2022.988304. eCollection 2022.
7
Efficacy of COVID-19 Vaccination in People Living with HIV: A Public Health Fundamental Tool for the Protection of Patients and the Correct Management of Infection.新冠病毒疫苗对HIV感染者的有效性：保护患者及正确管理感染的公共卫生基础工具
Infect Dis Rep. 2022 Oct 17;14(5):784-793. doi: 10.3390/idr14050080.
8
COVID-19 vaccine effectiveness among people living with and without HIV in South Carolina, USA: protocol of a population-based cohort study.美国南卡罗来纳州有和无艾滋病毒感染者的 COVID-19 疫苗有效性：基于人群的队列研究方案。
BMJ Open. 2022 Aug 23;12(8):e067095. doi: 10.1136/bmjopen-2022-067095.
9
Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition.未受抑制的 HIV 感染会损害 T 细胞对 SARS-CoV-2 感染的反应，并消除 T 细胞的交叉识别。
Elife. 2022 Jul 26;11:e78374. doi: 10.7554/eLife.78374.
10
Co-infection of Uropathogenic Escherichia coli among COVID-19 Patients Admitted to a Tertiary Care Centre: A Descriptive Cross-sectional Study.在一家三级护理中心住院的 COVID-19 患者中，同时感染尿路致病性大肠杆菌：一项描述性横断面研究。
JNMA J Nepal Med Assoc. 2022 Mar 11;60(247):294-298. doi: 10.31729/jnma.7376.
中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
4
Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43.针对严重急性呼吸综合征冠状病毒核衣壳蛋白产生的特异性抗体，与人类冠状病毒229E和OC43无交叉反应。
J Vet Sci. 2010 Jun;11(2):165-7. doi: 10.4142/jvs.2010.11.2.165.
5
The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients.2003年香港严重急性呼吸综合征疫情的流行病学：对1755例患者的分析。
Ann Intern Med. 2004 Nov 2;141(9):662-73. doi: 10.7326/0003-4819-141-9-200411020-00006.