Department of Dermatology, The Center For Cutaneous Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 375 Longwood Avenue, Boston, MA 02115, USA.
Department of Dermatology, The Center For Cutaneous Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 375 Longwood Avenue, Boston, MA 02115, USA.
Hematol Oncol Clin North Am. 2020 Jun;34(3):501-509. doi: 10.1016/j.hoc.2020.01.001. Epub 2020 Mar 20.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive malignancy derived from the plasmacytoid dendritic cell that commonly involves the skin. Cutaneous involvement is often the initial presentation, with deep purple or red-brown macules, plaques, or tumors. As such, dermatologists may be the first to see these patients and, in addition to oncologists, should be familiar with its presentation to facilitate early diagnosis, helping to distinguish it from acute myelogenous leukemia cutis.
原始细胞性浆细胞样树突细胞肿瘤（BPDCN）是一种罕见的侵袭性恶性肿瘤，来源于浆细胞样树突细胞，通常累及皮肤。皮肤受累通常是首发表现，表现为深紫色或红棕色斑疹、斑块或肿瘤。因此，皮肤科医生可能是首先看到这些患者的医生，除了肿瘤学家外，皮肤科医生也应该熟悉其表现，以促进早期诊断，帮助将其与急性髓系白血病皮肤浸润相区分。
