Liu Fang, Qi Fei, Zhang Jingya, Tan Yaqi, Zhang Xiuying
Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.
Department of Dermatology, Peking Union Medical College Hospital, Beijing, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Aug 11;16:2211-2216. doi: 10.2147/CCID.S414326. eCollection 2023.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a hostile cutaneous malignancy with dismal prognosis and unknown etiology with rarity. Most patients received traditional chemotherapy only has one year of median survival time. This article reports an 81-year-old male patient with BPDCN who presented with skin manifestations and was diagnosed with positive CD4, CD56, and CD123 immunohistochemical results. Systematic examination revealed lung involvement and cytopenia.
母细胞性浆细胞样树突状细胞肿瘤（BPDCN）是一种侵袭性皮肤恶性肿瘤，预后不佳，病因不明且较为罕见。大多数仅接受传统化疗的患者中位生存时间仅为一年。本文报告了一名81岁的BPDCN男性患者，该患者出现皮肤表现，免疫组化结果显示CD4、CD56和CD123呈阳性，经系统检查发现有肺部受累及血细胞减少。
