Prieto-Gómez Virginia, Yuste-Sánchez María José, Bailón-Cerezo Javier, Romay-Barrero Helena, de la Rosa-Díaz Irene, Lirio-Romero Cristina, Torres-Lacomba María
Physiotherapy in Women's Health (FPSM) Research Group, Physiotherapy Department, Faculty of Medicine and Health Sciences, University of Alcalá, 28805 Madrid, Spain.
Department of Nursery, Physiotherapy and Occupational Therapy, Faculty of Physiotherapy and Nursery, University of Castilla-La Mancha, 45071 Toledo, Spain.
J Clin Med. 2022 Jan 5;11(1):269. doi: 10.3390/jcm11010269.
This study aimed to determine the effectiveness of therapeutic exercise plus patient therapeutic education on perceived fatigue, functional capacity and pain in breast cancer survivors with cancer-related fatigue. A randomised, single-blind, clinical trial was conducted with a total of 80 breast cancer survivors who presented cancer-related fatigue. Women were randomised into a supervised therapeutic exercise group (STE-G) ( = 40) or an unsupervised exercise group (UE-G) ( = 40). Both interventions included patient therapeutic education and were delivered in three sessions per week over eight weeks. The main outcome was perceived fatigue as assessed by the Spanish version of the Functional Assessment of Chronic Illness Therapy-Fatigue subscale (FACIT-F). Other evaluated outcomes were pain measured on a visual analogue scale, and distance measured using the 6-Minute Walk Test. Data were collected at baseline, immediately post-intervention, and at three and six months after baseline. Significantly greater improvements across all variables were observed in the STE-G throughout the entire follow-up period with the exception of pain. Conclusions: A supervised therapeutic exercise program plus patient therapeutic education significantly reduce perceived fatigue and increase functional capacity in breast cancer survivors suffering from cancer-related fatigue compared to an unsupervised physical exercise program based on individual preferences with patient therapeutic education.
本研究旨在确定治疗性运动加患者治疗教育对患有癌症相关疲劳的乳腺癌幸存者的感知疲劳、功能能力和疼痛的有效性。对总共80名患有癌症相关疲劳的乳腺癌幸存者进行了一项随机、单盲临床试验。女性被随机分为监督治疗运动组（STE-G）（n = 40）或无监督运动组（UE-G）（n = 40）。两种干预措施均包括患者治疗教育，每周进行三次，共持续八周。主要结局是通过慢性疾病治疗功能评估疲劳分量表（FACIT-F）西班牙语版评估的感知疲劳。其他评估结局包括用视觉模拟量表测量的疼痛，以及用6分钟步行试验测量的距离。在基线、干预后立即以及基线后三个月和六个月收集数据。除疼痛外，在整个随访期间，STE-G在所有变量上均观察到显著更大的改善。结论：与基于个人偏好并结合患者治疗教育的无监督体育锻炼计划相比，监督治疗运动计划加患者治疗教育能显著降低患有癌症相关疲劳的乳腺癌幸存者的感知疲劳并提高其功能能力。
