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逆行性肾内手术治疗肾结石:土耳其泌尿外科协会前瞻性研究组(ACUP 研究)对结果的多方面批判性评估。

Retrograde intrarenal surgery of renal stones: a critical multi-aspect evaluation of the outcomes by the Turkish Academy of Urology Prospective Study Group (ACUP Study).

机构信息

Department of Urology, Istanbul Medipol University, TEM Otoyolu No. 1, Bagcilar, 34214, Istanbul, Turkey.

Department of Medical Statistics and Medical Informatics, Istanbul Medipol University, Istanbul, Turkey.

出版信息

World J Urol. 2021 Feb;39(2):549-554. doi: 10.1007/s00345-020-03210-2. Epub 2020 Apr 28.

DOI:10.1007/s00345-020-03210-2
PMID:32347334
Abstract

AIMS

To outline and evaluate the incidence, management and follow-up of the residual fragments (RFs) following retrograde intrarenal surgery (RIRS) of renal stones by the Turkish Academy of Urology Prospective Study Group (ACUP Study).

METHODS

Following the ethical committee approval, 15 centers providing data regarding the incidence, management, and follow-up of RFs after RIRS were included and all relevant information was recorded into the same electronic database program ( https://acup.uroturk.org.tr/ ) created by Turkish Urology Academy for Residual Stone Study.

RESULTS

A total of 1112 cases underwent RIRS for renal calculi and RFs were observed in 276 cases (24.8%). Of all the parameters evaluated, our results demonstrated no statistically significant relation between preoperative DJ stenting and the presence of RFs (χ2 (1) = 158.418; p = 0.099). RFs were significantly higher in patients treated with UAS (82 patients, 29.3%) during the procedure compared to the cases who did not receive UAS (194 patients, 23.3%) (χ2 (1) = 3.999; p = 0.046). The mean period for a secondary intervention after RIRS was 28.39 (± 12.52) days. Regarding the procedures applied for RF removal, re-RIRS was the most commonly performed approach (56%).

CONCLUSIONS

Despite the reported safe and successful outcomes, the incidence of RFs is higher, after the RIRS procedure particularly in cases with relatively larger calculi. Such cases need to be followed in a close manner and although a second flexible ureteroscopy is the treatment of choice for fragment removal in the majority of these patients, shock wave lithotripsy and percutaneous nephrolithotomy may also be preferred in selected cases.

摘要

目的

总结并评估土耳其泌尿外科协会前瞻性研究组(ACUP 研究)中经皮肾镜碎石术(RIRS)治疗肾结石后残石(RF)的发生率、处理方法和随访情况。

方法

在获得伦理委员会批准后,纳入了 15 个提供 RIRS 术后 RF 发生率、处理和随访相关数据的中心,并将所有相关信息记录到由土耳其泌尿外科协会创建的用于残留结石研究的同一电子数据库程序(https://acup.uroturk.org.tr/)中。

结果

共 1112 例肾结石患者接受了 RIRS 治疗,276 例(24.8%)患者发现 RF。在评估的所有参数中,我们的结果表明术前 DJ 支架置入与 RF 存在之间无统计学显著相关性(χ2(1)=158.418;p=0.099)。与未接受 UAS 治疗的患者(194 例,23.3%)相比,在手术中接受 UAS 治疗的患者(82 例,29.3%)的 RF 明显更高(χ2(1)=3.999;p=0.046)。RIRS 后进行二次干预的平均时间为 28.39(±12.52)天。关于 RF 清除的应用程序,再次 RIRS 是最常用的方法(56%)。

结论

尽管报告的结果安全且有效,但 RIRS 术后 RF 的发生率较高,尤其是在相对较大结石的病例中。这些病例需要密切随访,虽然大多数患者首选二次软性输尿管镜取石术治疗,但在某些情况下,也可选择体外冲击波碎石术和经皮肾镜碎石术。

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Curr Opin Urol. 2019 Mar;29(2):129-134. doi: 10.1097/MOU.0000000000000571.
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Is fluoroscopy-free single-use flexible ureteroscopy a feasible treatment for kidney stones with abnormal renal anatomy?
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