Ghiasvand Fereshteh, Miandoab Sepideh Zahak, Harandi Hamid, Golestan Fereshteh Shahmari, Alinaghi Seyed Ahmad Seyed
Liver Transplantation Research Center, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Infect Disord Drug Targets. 2020;20(4):559-562. doi: 10.2174/1871526520666200429115535.
After the initial outbreak of the new Coronavirus in Wuhan at the end of December 2019, many new cases were reported in other provinces of China and also many other countries over the world, including South Korea, Italy, Iran, Japan, and 68 other countries. We present a case report of a 61-year-old woman with a history of diabetes mellitus who was referred to the emergency department of a referral hospital in Tehran, Iran. The patient presented with fever, chills, and myalgia within three days. Laboratory analysis showed increased levels of erythrocyte sedimentation rate (ESR), and mild leukopenia. SARS-CoV-2 PCR test -under the Iran Ministry of Health and Medical Education (MoH&ME) guidelines- was conducted and the result was positive. The chest X-ray showed bilateral ground-glass opacity. O2 saturation was 87% (without O2 therapy). The patient was hospitalized and treated with Oseltamivir 75 mg every 12 hours, Lopinavir/Ritonavir (Kaletra) 400/100 mg every 12 hours and hydroxychloroquine 400 mg stat. The patient's last O2 saturation measured was 93% and she had no fever on the 10th day of hospitalization. Therefore, she was discharged from hospital and quarantined at home according to the Iran Ministry of Health protocol.
2019年12月底新型冠状病毒在武汉首次爆发后，中国其他省份以及世界上许多其他国家都报告了许多新病例，包括韩国、意大利、伊朗、日本以及其他68个国家。我们报告一例61岁患有糖尿病史的女性病例，该患者被转诊至伊朗德黑兰一家转诊医院的急诊科。患者在三天内出现发热、寒战和肌痛。实验室分析显示红细胞沉降率（ESR）升高，轻度白细胞减少。按照伊朗卫生和医学教育部（MoH&ME）的指导方针进行了SARS-CoV-2 PCR检测，结果呈阳性。胸部X线显示双侧磨玻璃影。氧饱和度为87%（未进行氧疗）。患者住院治疗，每12小时服用75毫克奥司他韦，每12小时服用400/100毫克洛匹那韦/利托那韦（克力芝），单次服用400毫克羟氯喹。患者最后一次测得氧饱和度为93%，住院第10天无发热。因此，她已出院，并按照伊朗卫生部的方案在家中隔离。
