Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Department of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA.
Am J Hematol. 2020 Aug;95(8):966-977. doi: 10.1002/ajh.25846. Epub 2020 May 18.
With rapid advancements in the diagnosis and treatment of multiple myeloma (MM), imaging has become instrumental in detection of intramedullary and extramedullary disease, providing prognostic information, and assessing therapeutic efficacy. Whole-body low dose computed tomography (WBLDCT) has emerged as the study of choice to detect osteolytic bone disease. Positron emission tomography/computed tomography (PET/CT) combines functional and morphologic information to identify MM disease activity and assess treatment response. Magnetic resonance imaging (MRI) has excellent soft-tissue contrast and is the modality of choice for bone marrow evaluation. This review focuses on the imaging modalities available for MM patient management, highlighting advantages, disadvantages, and applications of each.
随着多发性骨髓瘤 (MM) 的诊断和治疗的快速发展，影像学在检测骨髓内和骨髓外疾病、提供预后信息以及评估治疗效果方面变得至关重要。全身低剂量计算机断层扫描 (WBLDCT) 已成为检测溶骨性骨疾病的首选研究方法。正电子发射断层扫描/计算机断层扫描 (PET/CT) 结合了功能和形态学信息，以识别 MM 疾病活动并评估治疗反应。磁共振成像 (MRI) 具有出色的软组织对比度，是骨髓评估的首选方式。本文重点介绍了用于 MM 患者管理的影像学方式，强调了每种方式的优缺点及其应用。
