手臂骨骼肌量与肝硬化患者的预后相关。
Arm Skeletal Muscle Mass Is Associated With the Prognosis of Patients With Cirrhosis.
机构信息
Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
出版信息
In Vivo. 2020 May-Jun;34(3):1165-1171. doi: 10.21873/invivo.11889.
BACKGROUND/AIM: This study aimed to assess the clinical significance of measuring the arm skeletal muscle mass in patients with cirrhosis.
PATIENTS AND METHODS
Using body composition data measured with the bioimpedance analysis (BIA) method, the skeletal muscle mass index (SMI) values of the arm (arm skeletal muscle mass/height) and leg (leg skeletal mass muscle/height) were calculated for 353 patients with cirrhosis, and the relationships of these indices to their prognosis were assessed. In addition, overhydration of the upper and lower limbs was compared.
RESULTS
Arm SMI was significantly positively associated with the prognosis of patients with cirrhosis (p=0.0002) but leg SMI was not (p=0.0829). The rate of overhydration in the lower limbs was significantly higher than that in the upper limbs (p<0.0001).
CONCLUSION
Arm SMI measured with the BIA method was suggested to be minimally affected by water retention, and might be clinically useful for patients with cirrhosis.
背景/目的：本研究旨在评估测量肝硬化患者手臂骨骼肌量的临床意义。
患者与方法
使用生物电阻抗分析法（BIA）测量的身体成分数据，计算了 353 例肝硬化患者手臂（手臂骨骼肌量/身高）和腿部（腿部骨骼肌量/身高）的骨骼肌质量指数（SMI）值，并评估了这些指标与患者预后的关系。此外，比较了上下肢的水过多。
结果
手臂 SMI 与肝硬化患者的预后显著正相关（p=0.0002），但腿部 SMI 无显著相关性（p=0.0829）。下肢的水过多率明显高于上肢（p<0.0001）。
结论
BIA 法测量的手臂 SMI 受水潴留的影响较小，可能对肝硬化患者具有临床意义。
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