Fergusson D M, Fergusson J E, Horwood L J, Kinzett N G
Department of Paediatrics, Christchurch School of Medicine, Christchurch Public Hospital, New Zealand.
J Child Psychol Psychiatry. 1988 Nov;29(6):811-24. doi: 10.1111/j.1469-7610.1988.tb00755.x.
The relationship between dentine lead levels and maternal/teacher ratings of inattentive/restless behaviour in children was examined for a birth cohort of New Zealand children. There were small but relatively consistent and stable correlations between dentine lead values and behaviour ratings. After correction for errors of measurement in dentine lead values and behaviour ratings it was estimated that the correlation between lead levels and inattentive/restless behaviour was in the region of +0.18. However, after control for various sources of confounding there was only a small, but statistically significant, correlation of +0.08 between lead levels and inattention/restless in children. It is concluded that the weight of the evidence favours the view that there is a very weak causal association between lead levels and attention and activity levels in children.
针对一组新西兰儿童出生队列，研究了牙质铅含量与儿童注意力不集中/多动行为的母亲/教师评分之间的关系。牙质铅含量与行为评分之间存在虽小但相对一致且稳定的相关性。在校正牙质铅含量和行为评分的测量误差后，估计铅含量与注意力不集中/多动行为之间的相关性约为+0.18。然而，在控制各种混杂因素后，铅含量与儿童注意力不集中/多动之间仅存在微弱但具有统计学意义的+0.08的相关性。得出的结论是，现有证据倾向于认为铅含量与儿童注意力及活动水平之间存在非常微弱的因果关联。
