Opt Lett. 2020 May 1;45(9):2680-2683. doi: 10.1364/OL.389240.
Recent development of visible-light optical coherence tomography (vis-OCT) has introduced new applications for noninvasive spectroscopic imaging. However, the measured spectra may be altered by spectrally dependent roll-off (SDR). We formulated a mathematical model for SDR that accounted for nonuniform wavenumber spacing, optical aberrations, and misalignments in the spectrometer. We simulated SDR based on this model and found strong agreement with measurements from a vis-OCT system. We verified that SDR altered spectroscopic measurements of fully oxygenated blood. We corrected these alterations by normalizing each spectrally dependent A-line by the measured SDR of the spectrometer. Our investigations of SDR are critical for informing OCT spectrometer design, alignment, and spectroscopic measurements.
可见光学相干断层扫描（vis-OCT）的最新发展为非侵入性光谱成像引入了新的应用。然而，所测量的光谱可能会受到光谱相关滚降（SDR）的影响。我们为 SDR 制定了一个数学模型，该模型考虑了非均匀波数间距、光学像差和光谱仪中的不对准。我们基于该模型模拟了 SDR，并发现与 vis-OCT 系统的测量结果非常吻合。我们验证了 SDR 改变了完全氧合血液的光谱测量结果。我们通过用光谱仪测量的 SDR 对每条光谱相关的 A 线进行归一化来校正这些变化。我们对 SDR 的研究对于告知 OCT 光谱仪设计、对准和光谱测量非常重要。
