Department of Animal Production, NEIKER-BRTA, Basque Institute of Agricultural Research and Development, Agrifood Campus of Arkaute s/n, E-01080 Arkaute, Spain.
INRA, UMR 1388 GenPhySE, 31326 Castanet Tolosan, France.
J Dairy Sci. 2020 Jul;103(7):6346-6353. doi: 10.3168/jds.2019-18033. Epub 2020 Apr 29.
The availability of genomic marker panels has made possible more precise estimates of breeding values. Sheep breeding programs are implementing genomic selection. In Latxa dairy sheep breed, a previous study using pre-corrected data and a small number of genotyped animals did not show a clear advantage of genomic selection. The objective of the present study was to ascertain the possible benefits of GS for the Latxa breed based on more data than before and using better tools, in particular single-step genomic BLUP using metafounders to model missing pedigree. Goodness of prediction of pedigree and genomic evaluations was analyzed by cross-validation comparing predictions of young rams using whole and partial (truncated) data sets. The results showed that with the current available data, genetic and genomic evaluations have the same accuracy. Contrary to the previous study, predictions were nearly unbiased, which shows the advantage of using single-step genomic BLUP. However, genomic information did not yield more precise evaluations. This could be explained by the small number of sibs in the young rams.
基因组标记面板的可用性使得更精确的估计育种值成为可能。绵羊育种计划正在实施基因组选择。在拉塔克斯乳用绵羊品种中，先前的研究使用预校正数据和少量基因分型动物并没有显示基因组选择的明显优势。本研究的目的是基于比以前更多的数据和更好的工具，特别是使用元发现者对缺失系谱进行模型化的单步基因组 BLUP，确定 GS 对拉塔克斯品种的可能益处。通过使用完整和部分（截断）数据集比较年轻公羊的预测，分析系谱和基因组评估的预测准确性。结果表明，使用当前可用的数据，遗传和基因组评估具有相同的准确性。与之前的研究相反，预测几乎没有偏差，这表明使用单步基因组 BLUP 的优势。然而，基因组信息并没有产生更精确的评估。这可能是由于年轻公羊的同胎数较少。
