Balla Mamtha, Merugu Ganesh Prasad, Patel Mitra, Koduri Narayana Murty, Gayam Vijay, Adapa Sreedhar, Naramala Srikanth, Konala Venu Madhav
Department of Internal Medicine, University of Toledo and Promedica Toledo Hospital, Toledo, OH 43606, USA.
Division of Geriatric Medicine, Department of Family Medicine, University of Toledo, OH 43614, USA.
J Clin Med Res. 2020 Apr;12(4):215-229. doi: 10.14740/jocmr4142. Epub 2020 Mar 30.
Coronavirus disease 2019 (COVID-19) caused infection in 168,000 cases worldwide in about 148 countries and killed more than 6,610 people around the world as of March 16, 2020, as per the World Health Organization (WHO). Compared to severe acute respiratory syndrome and Middle East respiratory syndrome, there is the rapid transmission, long incubation period, and disease containment is becoming extremely difficult. The main aim of this systematic review is to provide a comprehensive clinical summary of all the available data from high-quality research articles relevant to the epidemiology, demographics, trends in hospitalization and outcomes, clinical signs and symptoms, diagnostic methods and treatment methods of COVID-19, thus increasing awareness in health care providers. We also discussed various preventive measures to combat COVID-19 effectively. A systematic and protocol-driven approach is needed to contain this disease, which was declared as a global pandemic on March 11, 2020, by the WHO.
根据世界卫生组织（WHO）的数据，截至2020年3月16日，2019冠状病毒病（COVID-19）在全球约148个国家感染了16.8万例，导致全球6610多人死亡。与严重急性呼吸综合征和中东呼吸综合征相比，COVID-19具有传播迅速、潜伏期长的特点，疾病控制变得极为困难。本系统综述的主要目的是对高质量研究文章中所有与COVID-19的流行病学、人口统计学、住院趋势和结局、临床体征和症状、诊断方法及治疗方法相关的可用数据进行全面的临床总结，从而提高医疗服务提供者的认识。我们还讨论了有效抗击COVID-19的各种预防措施。需要采用系统且遵循方案的方法来控制这种于2020年3月11日被WHO宣布为全球大流行的疾病。
