Hirshberg A, Leibovich P, Buchner A
Department of Oral Pathology and Oral Medicine, Maurice and Gabriela School of Dental Medicine, Tel Aviv University, Israel.
J Oral Pathol Med. 1993 Oct;22(9):385-90. doi: 10.1111/j.1600-0714.1993.tb00128.x.
A review of the English-language literature revealed 157 well-documented cases of metastatic lesions to the oral mucosa. Most (64%) were diagnosed in patients in their fifth to seventh decade. The frequency of the primary site differed between genders: for men it was the lung (35.5%) followed by the kidney (16%) and skin (15%); for women it was the breast (24%) followed by the genital organs (17%). The most common oral site was the gingiva and alveolar mucosa (54.8%) followed by the tongue (27.4%), and with much less frequency by the tonsil, palate, lip, buccal mucosa and floor of the mouth. Of the dentulous patients, 79% exhibited the metastatic tumor in the attached gingiva. The clinical appearance of the metastatic oral lesion in most cases resembled hyperplastic or reactive lesions.
对英文文献的回顾显示，有157例记录详实的口腔黏膜转移瘤病例。大多数（64%）患者在50至70岁之间被诊断出来。原发部位的频率在性别上有所不同：男性为肺部（35.5%），其次是肾脏（16%）和皮肤（15%）；女性为乳腺（24%），其次是生殖器官（17%）。最常见的口腔部位是牙龈和牙槽黏膜（54.8%），其次是舌头（27.4%），而扁桃体、腭、唇、颊黏膜和口底的发生率则低得多。在有牙患者中，79%的转移瘤出现在附着龈。大多数情况下，口腔转移瘤的临床表现类似于增生性或反应性病变。
