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膳食暴露评估:突尼斯 19 至 65 岁成年人口的农药残留摄入量。

Dietary exposure of Tunisian adult population aged from 19 to 65 years old to pesticides residues.

机构信息

Product Sanitary Control Department, National Agency for Product Sanitary and Environmental Control (ANCSEP) , Tunis, Tunisia.

Biological Sciences, Faculty of Sciences of Bizerte , Bizerte, Tunisia.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2020 Jul;37(7):1165-1179. doi: 10.1080/19440049.2020.1744065. Epub 2020 May 3.

DOI:10.1080/19440049.2020.1744065
PMID:32364019
Abstract

Dietary exposure of the Tunisian adult population to pesticide residue was assessed using the Total Diet Study method. In the present study 170 pesticides were searched for in 42 aggregated foods characterised by 64 food samples representing the Tunisian diet. All the food samples were collected, prepared, and analysed for remains of pesticides including organochlorine, organophosphorous, carbamates and pyrethroids. The GC-MS analysis and the LC-MS/MS analysis and some other specific analytical methods were employed for the quantification of the pesticide residues in the food samples. Results revealed that21pesticides reached amounts greater than the LOQ(12.3%) and 149 pesticides reached amounts below the LOD (88%).For the 21 pesticides quantified, the ADI was not exceeded. For the 149 non-quantified pesticides, an interval defined by the lower and upper bounds was defined to assess the dietary exposure of the Tunisian adult population to those pesticides. We conclude that 8 pesticides theoretically exceed the ADI with the 95 percentile of exposure, those are: Diféthialone, Brodifacoum, Bromadiolone, Glufosinate, Heptachlor, Dieldrin Aldrin Oxydemeton-methyl. This study concludes that there is a low dietary exposure to pesticide residue of the Tunisian adult population. In fact, all the cases where the ADI was exceeded were theoretical due to the lower ADI value used.

摘要

采用总膳食研究方法评估了突尼斯成年人的饮食中农药残留的暴露情况。在本研究中,在 64 种具有代表性的突尼斯饮食的食物样本中,对 42 种聚合食物中 170 种农药进行了搜索。所有的食物样本都被采集、制备并分析了农药残留,包括有机氯、有机磷、氨基甲酸酯和拟除虫菊酯。采用 GC-MS 分析、LC-MS/MS 分析和其他一些特定的分析方法对食物样本中的农药残留进行定量分析。结果表明,21 种农药的残留量超过了定量下限(12.3%),149 种农药的残留量低于检测限(88%)。对于 21 种定量的农药,ADI 未超标。对于 149 种未定量的农药,通过定义上下限来评估突尼斯成年人对这些农药的饮食暴露情况。我们得出结论,有 8 种农药理论上超过了 ADI,其 95%的暴露值是:Diféthialone、Brodifacoum、Bromadiolone、Glufosinate、Heptachlor、Dieldrin、Aldrin、Oxydemeton-methyl。本研究表明,突尼斯成年人的饮食中农药残留的暴露水平较低。事实上,所有 ADI 超标的情况都是由于使用了较低的 ADI 值而产生的理论值。

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