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作为抗菌剂的天然化合物

Natural Compounds as Antimicrobial Agents.

作者信息

Franco Carlos Manuel, Vázquez Beatriz I

机构信息

Hygiene, Inspection and Food Control Laboratory, Analytical Chemistry, Nutrition and Bromatology Department, Faculty of Veterinary, University of Santiago de Compostela, 27002 Lugo, Spain.

出版信息

Antibiotics (Basel). 2020 Apr 29;9(5):217. doi: 10.3390/antibiotics9050217.

DOI:10.3390/antibiotics9050217
PMID:32365458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7277449/
Abstract

During the first two decades of this century, conventional antimicrobial compounds have been found out to have more bacterial resistance. What has also been worrying is the rediscovery of the so-called "natural compounds", which in turn have a good name among the average citizen because of the former's plant or animal origin. However, they do not form a well-classified group of substances. This Special Issue consists of five reviews focusing on clinical bacteria applications in food and their specific effects upon virulent bacterial factors. You will also find a research on much needed, new antimicrobials sourced in extreme environments, and secondary metabolites of . This issue includes 12 original research papers which will provide you with an in-depth coverage of the protein extract activity, as well as the activity of other plant extracts, on fighting bacteria, fungi or diarrhea. Their use in broilers or laying eggs for production purposes has also been focused on in order to improve gut microbiota. Last but not least, we should not forget about honey and its effect; Allium sativum-fermented extracts, as well as other "natural" compounds, have been studied in their fight against biofilms. Furthermore, we have also examined the use of essential oils, which are currently used in edibles such as fresh sausages. The present work also deals with other applications such as natural compound derivatives as well as compound mixtures.

摘要

在本世纪的前二十年里,人们发现传统抗菌化合物的细菌耐药性更强。同样令人担忧的是所谓“天然化合物”的重新发现,由于其植物或动物来源,这些化合物在普通民众中颇受青睐。然而,它们并非一类分类明确的物质。本期特刊包含五篇综述,聚焦食品中的临床细菌应用及其对致病性细菌因子的特定影响。你还会看到一项关于从极端环境中获取急需的新型抗菌剂以及[此处原文缺失部分内容]的次级代谢产物的研究。本期包括12篇原创研究论文,将为你深入介绍蛋白质提取物活性以及其他植物提取物在对抗细菌、真菌或腹泻方面的活性。为改善肠道微生物群,还重点研究了它们在肉鸡或产蛋鸡生产中的应用。最后但同样重要的是,我们不应忘记蜂蜜及其作用;大蒜发酵提取物以及其他“天然”化合物在对抗生物膜方面的研究情况。此外,我们还研究了目前用于新鲜香肠等食品中的精油的使用情况。本研究还涉及其他应用,如天然化合物衍生物以及化合物混合物。

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本文引用的文献

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The Bactericidal Activity of Protein Extracts from Berries: A Natural Resource of Bioactive Compounds.浆果蛋白质提取物的杀菌活性:生物活性化合物的天然来源
Antibiotics (Basel). 2020 Jan 28;9(2):47. doi: 10.3390/antibiotics9020047.
2
Honey as a Strategy to Fight in Mixed-Biofilms with .蜂蜜作为对抗含……的混合生物膜的一种策略。
Antibiotics (Basel). 2020 Jan 21;9(2):43. doi: 10.3390/antibiotics9020043.
3
Effects of Dietary Chicory ( L.) and Probiotic Blend as Natural Feed Additives on Performance Traits, Blood Biochemistry, and Gut Microbiota of Broiler Chickens.日粮菊苣及益生菌混合物作为天然饲料添加剂对肉鸡生产性能、血液生化指标和肠道微生物群的影响
Antibiotics (Basel). 2019 Dec 20;9(1):5. doi: 10.3390/antibiotics9010005.
4
Short Chain Fatty Acids Commonly Produced by Gut Microbiota Influence Motility, Biofilm Formation, and Gene Expression.肠道微生物群通常产生的短链脂肪酸会影响运动性、生物膜形成和基因表达。
Antibiotics (Basel). 2019 Dec 13;8(4):265. doi: 10.3390/antibiotics8040265.
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Prevention of Biofilm Formation on Soft Contact Lenses by Fermented Extract (BGE) and Cannabinol Oil Extract (CBD).发酵提取物(BGE)和大麻酚油提取物(CBD)对软性隐形眼镜生物膜形成的预防作用
Antibiotics (Basel). 2019 Dec 10;8(4):258. doi: 10.3390/antibiotics8040258.
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