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皮肤疾病在 COVID-19 之前的表现:银屑病和浅部真菌感染患者是否更容易感染 COVID-19?

Dermatological diseases presented before COVID-19: Are patients with psoriasis and superficial fungal infections more vulnerable to the COVID-19?

机构信息

Uşak University, Department of Dermatology and Venereology, School of Medicine, Uşak, Turkey.

出版信息

Dermatol Ther. 2020 Jul;33(4):e13509. doi: 10.1111/dth.13509. Epub 2020 Jun 3.

Abstract

Recent studies have focused on the comorbid conditions of the COVID-19. According to the current studies, numerous diseases including lung disease, cardiovascular disease and immunosuppression appear to be at higher risk for severe forms of the COVID-19. To date, there are no data in the literature on the comorbid dermatologic diseases and COVID-19. We tried to analyze the previous dermatological comorbidity of 93 patients with COVID-19 (51 males, 42 females) who presented to the dermatology outpatient clinics for the last 3 years. The most common dermatologic diseases in patients with COVID-19 who have dermatologic diseases for the last 3 years were superficial fungal infections (24, 25.8%), seborrheic dermatitis (11, 11.8%), actinic keratosis (10, 10.8%), psoriasis (6, 6.5%), and eczema (6, 6.5%), respectively. In addition, the number of COVID-19 patients who presented to dermatology in the last 3 months was 17 (11 men, 6 women). The median age of these patients was 58 (minimum 18, maximum 80) years, and the most common dermatologic diseases before diagnosed COVID-19 were superficial fungal infections (5, 25%), psoriasis (4, 20%), and viral skin diseases (3, 15%). The possible similarity between cutaneous and mucosal immunity and immunosuppression suggests that patients with some dermatologic diseases especially superficial fungal infections and psoriasis may be more vulnerable to the COVID-19.

摘要

最近的研究集中在 COVID-19 的合并症上。根据目前的研究,许多疾病,包括肺部疾病、心血管疾病和免疫抑制,似乎患 COVID-19 严重形式的风险更高。迄今为止,文献中尚无关于合并皮肤病和 COVID-19 的数据。我们试图分析过去 3 年来在皮肤科门诊就诊的 93 名 COVID-19 患者(51 名男性,42 名女性)的先前皮肤科合并症。过去 3 年来患有皮肤病的 COVID-19 患者中最常见的皮肤病是浅部真菌感染(24 例,25.8%)、脂溢性皮炎(11 例,11.8%)、光化性角化病(10 例,10.8%)、银屑病(6 例,6.5%)和湿疹(6 例,6.5%)。此外,过去 3 个月内到皮肤科就诊的 COVID-19 患者有 17 例(11 名男性,6 名女性)。这些患者的中位年龄为 58 岁(最小 18 岁,最大 80 岁),在确诊 COVID-19 之前最常见的皮肤病是浅部真菌感染(5 例,25%)、银屑病(4 例,20%)和病毒性皮肤病(3 例,15%)。皮肤和粘膜免疫及免疫抑制之间可能存在相似性,这表明某些皮肤病患者,特别是浅部真菌感染和银屑病患者,可能更容易感染 COVID-19。

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