Sharma Rajeev, Das Prasenjit, Kairo Arvind, Kale Shashank S
Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
J Neurosci Rural Pract. 2020 Apr;11(2):349-352. doi: 10.1055/s-0040-1709249. Epub 2020 May 2.
Drug-induced gingival overgrowth (DIGO) secondary to chronic phenytoin intake for seizure control is a well-recognized phenomenon. Phenytoin-induced gingival overgrowth (PIGO) usually resolves gradually following cessation of phenytoin intake. It is usually seen throughout the dentate regions of the maxillary and mandibular dental arches, but more severely affect their anterior portions exposed to atmosphere. We report a rare case of PIGO predominantly involving hard palate and floor of oral cavity, which has not been reported in English literature till date.
因长期服用苯妥英钠控制癫痫发作而导致的药物性牙龈增生（DIGO）是一种广为人知的现象。苯妥英钠所致牙龈增生（PIGO）通常在停用苯妥英钠后逐渐消退。它通常见于上颌和下颌牙弓的有牙区域，但对暴露于空气中的前部影响更为严重。我们报告一例罕见的PIGO病例，主要累及硬腭和口腔底部，迄今为止英文文献中尚无此类报道。
