5-Aminosalicylic acid in patients with ulcerative colitis in remission: plasma levels after administration of a new rectal enema.
作者信息
Gionchetti P, Belluzzi A, Campieri M, Torresan F, Tabanelli G M, Brignola C, Miglioli M, Barbara L
机构信息
Istituto di Clinica Medica e Gastroenterologia, Policlinico S. Orsola, Bologna, Italy.
出版信息
Methods Find Exp Clin Pharmacol. 1988 Oct;10(10):667-9.
PMID:3236941
Abstract
Plasma levels of total 5-aminosalicylic acid (5-ASA) were determined after a single administration of 2 g and 4 g 5-ASA enemas to 6 patients with ulcerative colitis. The mean plasma levels and AUC values confirmed that the active substance is poorly absorbed by rectal route.
摘要
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