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利用生物信号处理和深度学习识别睡眠相关障碍患者群体。

Recognition of Patient Groups with Sleep Related Disorders using Bio-signal Processing and Deep Learning.

机构信息

Smart Health Technologies Group, School of Computer Science and Electronic Engineering; University of Essex, Colchester CO4 3SQ, UK.

Embedded and Intelligent Systems Laboratory, School of Computer Science and Electronics, University of Essex, Colchester CO4 3SQ, UK.

出版信息

Sensors (Basel). 2020 May 2;20(9):2594. doi: 10.3390/s20092594.

Abstract

Accurately diagnosing sleep disorders is essential for clinical assessments and treatments. Polysomnography (PSG) has long been used for detection of various sleep disorders. In this research, electrocardiography (ECG) and electromayography (EMG) have been used for recognition of breathing and movement-related sleep disorders. Bio-signal processing has been performed by extracting EMG features exploiting entropy and statistical moments, in addition to developing an iterative pulse peak detection algorithm using synchrosqueezed wavelet transform (SSWT) for reliable extraction of heart rate and breathing-related features from ECG. A deep learning framework has been designed to incorporate EMG and ECG features. The framework has been used to classify four groups: healthy subjects, patients with obstructive sleep apnea (OSA), patients with restless leg syndrome (RLS) and patients with both OSA and RLS. The proposed deep learning framework produced a mean accuracy of 72% and weighted F1 score of 0.57 across subjects for our formulated four-class problem.

摘要

准确诊断睡眠障碍对于临床评估和治疗至关重要。多导睡眠图(PSG)长期以来一直用于检测各种睡眠障碍。在这项研究中,心电图(ECG)和肌电图(EMG)已被用于识别与呼吸和运动相关的睡眠障碍。通过提取 EMG 特征并利用熵和统计矩进行生物信号处理,除了开发一种使用同步挤压小波变换(SSWT)的迭代脉冲峰检测算法以从 ECG 中可靠地提取心率和呼吸相关特征外,还进行了生物信号处理。设计了一个深度学习框架来合并 EMG 和 ECG 特征。该框架用于对四个组进行分类:健康受试者、阻塞性睡眠呼吸暂停(OSA)患者、不安腿综合征(RLS)患者以及 OSA 和 RLS 均有的患者。对于我们提出的四组问题,所提出的深度学习框架在所有受试者中的平均准确率为 72%,加权 F1 分数为 0.57。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2998/7248846/250ca034bfd9/sensors-20-02594-g001.jpg

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