Khan Wajid Ali, Arain Muhammad Balal, Yamini Yadollah, Shah Nasrullah, Kazi Tasneem Gul, Pedersen-Bjergaard Stig, Tajik Mohammad
Department of Chemistry, Abdul Wali Khan University Mardan, 23200, KPK, Pakistan.
Department of Chemistry, University of Karachi, 75270, Karachi, Pakistan.
J Pharm Anal. 2020 Apr;10(2):109-122. doi: 10.1016/j.jpha.2019.12.003. Epub 2019 Dec 12.
Hollow-fiber liquid-phase microextraction (HF-LPME) and electromembrane extraction (EME) are miniaturized extraction techniques, and have been coupled with various analytical instruments for trace analysis of heavy metals, drugs and other organic compounds, in recent years. HF-LPME and EME provide high selectivity, efficient sample cleanup and enrichment, and reduce the consumption of organic solvents to a few micro-liters per sample. HF-LPME and EME are compatible with different analytical instruments for chromatography, electrophoresis, atomic spectroscopy, mass spectrometry, and electrochemical detection. HF-LPME and EME have gained significant popularity during the recent years. This review focuses on hollow fiber based techniques (especially HF-LPME and EME) of heavy metals and pharmaceuticals (published 2017 to May 2019), and their combinations with atomic spectroscopy, UV-VIS spectrophotometry, high performance liquid chromatography, gas chromatography, capillary electrophoresis, and voltammetry.
中空纤维液相微萃取（HF-LPME）和电膜萃取（EME）是微型化萃取技术，近年来已与各种分析仪器联用，用于重金属、药物及其他有机化合物的痕量分析。HF-LPME和EME具有高选择性、高效的样品净化和富集能力，且每个样品的有机溶剂消耗量可降至几微升。HF-LPME和EME可与用于色谱分析、电泳、原子光谱、质谱及电化学检测的不同分析仪器兼容。近年来，HF-LPME和EME已颇受关注。本综述聚焦于2017年至2019年5月期间发表的基于中空纤维的重金属和药物分析技术（尤其是HF-LPME和EME），以及它们与原子光谱、紫外可见分光光度法、高效液相色谱、气相色谱、毛细管电泳和伏安法的联用。
