Bashyam A, Grammatopoulou V, Crook T, Di Palma S, Sunkaraneni V S
Ear, Nose and Throat Department, Royal Surrey County Hospital, Guildford, Surrey, UK.
Oncology Department, Royal Surrey County Hospital, Guildford, Surrey, UK.
Ann R Coll Surg Engl. 2020 Jul;102(6):e118-e121. doi: 10.1308/rcsann.2020.0038. Epub 2020 May 6.
Tumour-to-tumour metastasis is a rare phenomenon. It occurs when a primary tumour is a recipient of a separate tumour within the same individual. We present a case of a 66-year-old woman with known breast cancer who presented with one-sided nasal symptoms. Examination and imaging revealed a unilateral polyp arising from the skull base. She underwent endoscopic polypectomy with the histology demonstrating tumour-to-tumour metastasis from a breast carcinoma to an olfactory neuroblastoma, a rare sinonasal tumour. Clinicians should be cautious of distant metastases in any patient presenting with head and neck symptoms and a known primary tumour. This is the first documented case of this type.
肿瘤-to-肿瘤转移是一种罕见现象。当原发性肿瘤成为同一个体内另一个独立肿瘤的接受者时，就会发生这种情况。我们报告一例66岁已知患有乳腺癌的女性，她出现单侧鼻部症状。检查和影像学检查发现一个源于颅底的单侧息肉。她接受了内镜下息肉切除术，组织学检查显示为从乳腺癌转移至嗅神经母细胞瘤的肿瘤-to-肿瘤转移，嗅神经母细胞瘤是一种罕见的鼻窦肿瘤。对于任何出现头颈部症状且已知患有原发性肿瘤的患者，临床医生都应警惕远处转移。这是此类有记录的首例病例。
