Pham Jason T, Kim Ronald C, Nguyen Anna, Bota Daniela, Kong Xiao-Tang, Vadera Sumeet, Hsu Frank, Carrillo Jose A
Department of Neurology, University of California, Irvine Medical Center, Orange, CA 92868, USA.
Department of Neuropathology, University of California, Irvine Medical Center, Orange, CA 92868, USA.
CNS Oncol. 2018 Apr;7(2):CNS09. doi: 10.2217/cns-2017-0022. Epub 2018 Apr 26.
Meningiomas have been implicated as the most common primary intracranial tumor to contain tumor-to-tumor metastasis. In the following two case reports, we describe cases of adenocarcinoma and breast carcinoma that metastasized into an intracranial meningioma. The first patient was a 64-year-old man presenting to the emergency department with seizures and loss of consciousness. After a left frontal mass resection, pathology reported a heterogeneous mass consisting of a meningioma and a metastatic adenocarcinoma component. The second patient was a 63-year-old woman presenting with significant vision problems and unstable gait. After a right frontal mass resection, pathology reported a heterogeneous mass consisting of a meningioma and a metastatic breast carcinoma component. Possible explanations for the development of the tumor-to-tumor metastasis are described.
脑膜瘤被认为是最常见的发生肿瘤至肿瘤转移的原发性颅内肿瘤。在以下两个病例报告中，我们描述了转移至颅内脑膜瘤的腺癌和乳腺癌病例。首例患者为一名64岁男性，因癫痫发作和意识丧失就诊于急诊科。左额叶肿物切除术后，病理报告显示为一个由脑膜瘤和转移性腺癌成分组成的异质性肿物。第二例患者为一名63岁女性，出现严重视力问题和步态不稳。右额叶肿物切除术后，病理报告显示为一个由脑膜瘤和转移性乳腺癌成分组成的异质性肿物。文中描述了肿瘤至肿瘤转移发生的可能原因。
