Shiri Rahman, Lallukka Tea, Rahkonen Ossi, Leino-Arjas Päivi
Finnish Institute of Occupational Health, Helsinki, Finland.
Department of Public Health, University of Helsinki, Helsinki, Finland.
Pain Med. 2020 Nov 1;21(11):3094-3101. doi: 10.1093/pm/pnaa102.
To estimate the effects of excess body mass and leisure time physical activity on the incidence and persistence of chronic pain.
A prospective cohort study.
As a part of the Finnish Helsinki Health Study, we included three cohorts of employees of the City of Helsinki (18,562 observations) and defined incident chronic pain as having pain in any part of the body for more than three months at follow-up in participants without chronic pain at baseline (N = 13,029 observations). Persistent chronic pain was defined as having pain for more than three months at both baseline and follow-up (N = 5,533 observations).
Overweight (adjusted odds ratio [OR] = 1.18, 95% confidence interval [CI] = 1.06-1.31) and obesity (OR = 1.65, 95% CI = 1.45-1.88) increased the incidence of chronic pain. Moreover, overweight (OR = 1.16, 95% CI = 1.02-1.32) and obesity (OR = 1.48, 95% CI = 1.26-1.74) increased the risk of persistent chronic pain. Vigorous leisure time physical activity reduced the incidence of chronic pain (OR = 0.85, 95% CI = 0.75-0.96). Physical activity did not influence the risk of persistent chronic pain. Furthermore, overweight/obesity modified the effect of leisure time physical activity on incident chronic pain. Inactive overweight or obese participants were at the highest risk of chronic pain (OR = 1.71, 95% CI = 1.40-2.09), while the OR dropped to 1.44 (95% CI = 1.19-1.75) in moderately active overweight or obese participants and to 1.20 (95% CI = 0.97-1.47) in highly active overweight or obese participants.
Obesity not only increases the risk of developing chronic pain, but also increases the risk of persistent pain, while leisure time physical activity reduces the risk of developing chronic pain.
评估超重和休闲时间体力活动对慢性疼痛的发生率和持续性的影响。
一项前瞻性队列研究。
作为芬兰赫尔辛基健康研究的一部分,我们纳入了赫尔辛基市的三组员工队列(18562条观察数据),并将新发慢性疼痛定义为在基线时无慢性疼痛的参与者在随访时身体任何部位疼痛超过三个月(N = 13029条观察数据)。持续性慢性疼痛定义为在基线和随访时均有疼痛超过三个月(N = 5533条观察数据)。
超重(调整后的优势比[OR]=1.18,95%置信区间[CI]=1.06 - 1.31)和肥胖(OR = 1.65,95% CI = 1.45 - 1.88)会增加慢性疼痛的发生率。此外,超重(OR = 1.16,95% CI = 1.02 - 1.32)和肥胖(OR = 1.48,95% CI = 1.26 - 1.74)会增加持续性慢性疼痛的风险。剧烈休闲时间体力活动可降低慢性疼痛的发生率(OR = 0.85,95% CI = 0.75 - 0.96)。体力活动对持续性慢性疼痛的风险没有影响。此外,超重/肥胖改变了休闲时间体力活动对新发慢性疼痛的影响。不活动的超重或肥胖参与者患慢性疼痛的风险最高(OR = 1.71,95% CI = 1.40 - 2.09),而中度活动的超重或肥胖参与者的OR降至1.44(95% CI = 1.19 - 1.75),高度活动的超重或肥胖参与者的OR降至1.20(95% CI = 0.97 - 1.47)。
肥胖不仅会增加患慢性疼痛的风险,还会增加持续性疼痛的风险,而休闲时间体力活动可降低患慢性疼痛的风险。