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草药混合物输注物作为酚类化合物和生物活性特性的有前途的来源。

Infusions of Herbal Blends as Promising Sources of Phenolic Compounds and Bioactive Properties.

机构信息

Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.

CITAB-University of Trás-os-Montes and Alto Douro (UTAD), Department of Agronomy, 5001-801 Vila Real, Portugal.

出版信息

Molecules. 2020 May 4;25(9):2151. doi: 10.3390/molecules25092151.

Abstract

Several plants have been used for medicinal applications and have been traditionally consumed as decoctions and infusions. Although some herbs are used alone as a beverage, they are often blended in mixtures to maximize their effects. Herein, the nutritional characterization of six infusions from herbal blends was evaluated using the official methods of analysis (AOAC international). A further characterization of the individual phenolic profile was also performed by HPLC-DAD/ESI-MSn, and finally bioactive potential was determined by evaluating the antioxidant, cytotoxic, anti-inflammatory, and antimicrobial activities of each blend. The wide variety of plants in each sample led to variability in the results for all analyzed parameters. However, blends containing 15% L. and 15% L. in their composition showed higher sugar content and energy contribution; higher concentration of phenolic compounds (phenolic acids and flavonoids); greater antioxidant, cytotoxic, and anti-inflammatory capacity; and also better antimicrobial effects against all the tested bacterial and fungal strains. Further studies will be necessary to evaluate the real synergistic effects that these two species show in the presence of other plants, and to evaluate their potential for application in various food, pharmaceutical, and nutraceutical products as infusion preparations.

摘要

几种植物已被用于药用,并已被传统地用作汤剂和浸剂。虽然有些草药单独用作饮料,但它们经常混合在混合物中以最大限度地发挥其效果。在此,使用官方分析方法(AOAC 国际)评估了六种草药混合物的浸剂的营养特性。还通过 HPLC-DAD/ESI-MSn 进一步对各混合物的个体酚类图谱进行了表征,最后通过评估各混合物的抗氧化、细胞毒性、抗炎和抗菌活性来确定其生物活性潜力。由于每个样品中的植物种类繁多,导致所有分析参数的结果都存在差异。然而,在其组成中含有 15% L. 和 15% L. 的混合物显示出更高的糖含量和能量贡献;更高浓度的酚类化合物(酚酸和类黄酮);更强的抗氧化、细胞毒性和抗炎能力;对所有测试的细菌和真菌菌株也具有更好的抗菌作用。需要进一步研究以评估这两种物质在存在其他植物时显示的真实协同作用,并评估它们作为浸剂制剂在各种食品、制药和营养保健品中的应用潜力。

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