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宏量营养素组成与最年长男性的肌肉减少症:赫尔辛基商人研究(HBS)。

Macronutrient composition and sarcopenia in the oldest-old men: The Helsinki Businessmen Study (HBS).

机构信息

University of Helsinki, Department of General Practice and Primary Health Care, and Helsinki University Central Hospital, Unit of Primary Health Care, Finland.

University of Helsinki, Department of General Practice and Primary Health Care, and Helsinki University Central Hospital, Unit of Primary Health Care, Finland.

出版信息

Clin Nutr. 2020 Dec;39(12):3839-3841. doi: 10.1016/j.clnu.2020.04.024. Epub 2020 Apr 24.

DOI:10.1016/j.clnu.2020.04.024
PMID:32376097
Abstract

BACKGROUND & AIM: Sarcopenia is associated with increased risk for several adverse health outcomes including frailty, disability, loss of independence, and mortality. We examined cross-sectional associations between sarcopenia and detailed dietary macronutrient composition in community-living oldest-old men (mean age 87).

METHODS

Participants were invited to a clinic visit in 2017/2018 including assessments of sarcopenia status using European Working Group on Sarcopenia in Older People's 2 (EWGSOP2) criteria and detailed macronutrient, vitamin D and food intakes retrieved from 3-day food diaries.

RESULTS

Of the 126 participants, 48 had probable sarcopenia and 27 sarcopenia. Sarcopenia was associated with lower energy (p = 0.020), total protein (p = 0.019), plant (p = 0.008) and fish proteins (p = 0.041), total fat (p = 0.015), monounsaturated fatty acids (MUFA) (p = 0.011), polyunsaturated fatty acids (p = 0.002), vitamin D intakes (p = 0.005) and, of fat quality indicators, MUFA: saturated fatty acid-ratio (p = 0.042).

CONCLUSION

These findings suggest that sufficient energy and protein intakes, but also fat quality may be important along with healthy dietary patterns for prevention of sarcopenia in the oldest-old.

摘要

背景与目的

肌少症与多种不良健康结果相关,包括虚弱、残疾、丧失独立性和死亡。我们研究了社区居住的高龄男性(平均年龄 87 岁)肌少症与详细饮食宏量营养素组成之间的横断面关联。

方法

邀请参与者在 2017/2018 年参加诊所就诊,包括使用欧洲老年人肌少症工作组 2(EWGSOP2)标准评估肌少症状态,以及从 3 天饮食日记中获取详细的宏量营养素、维生素 D 和食物摄入量。

结果

在 126 名参与者中,48 名可能患有肌少症,27 名患有肌少症。肌少症与能量摄入较低(p=0.020)、总蛋白(p=0.019)、植物蛋白(p=0.008)和鱼类蛋白(p=0.041)、总脂肪(p=0.015)、单不饱和脂肪酸(MUFA)(p=0.011)、多不饱和脂肪酸(p=0.002)、维生素 D 摄入量(p=0.005)以及脂肪质量指标中的 MUFA:饱和脂肪酸比(p=0.042)有关。

结论

这些发现表明,充足的能量和蛋白质摄入,以及良好的脂肪质量,可能与健康的饮食模式一起,对预防高龄人群的肌少症很重要。

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