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饮食中维生素 E 和脂肪的摄入量与社区居住的日本老年人肌少症的关系:来自 ROAD 研究第五次调查的横断面研究。

Dietary Intake of Vitamin E and Fats Associated with Sarcopenia in Community-Dwelling Older Japanese People: A Cross-Sectional Study from the Fifth Survey of the ROAD Study.

机构信息

Institute for Health Care Science, Suntory Wellness Limited, 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto 619-0284, Japan.

Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical & Research Center, The University of Tokyo Hospital, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

Nutrients. 2021 May 20;13(5):1730. doi: 10.3390/nu13051730.

Abstract

Dietary habits are of considerable interest as a modifiable factor for the maintenance of muscle health, especially sarcopenia. The present study aimed to investigate the association between dietary intake and sarcopenia prevalence in community-dwelling Japanese subjects. This cross-sectional study was conducted using data from the fifth survey of the Research on Osteoarthritis/Osteoporosis against Disability (ROAD) study, and 1345 participants (437 men and 908 women) aged ≥60 years were included in the analysis. Sarcopenia was determined by the definition of the Asian Working Group for Sarcopenia established in 2014, and dietary intake was assessed with the brief-type self-administered diet history questionnaire. Overall, 77 subjects (5.7%) were identified as having sarcopenia, 5.0% of men and 6.1% of women. Multiple logistic regression analysis showed that the odds ratios of sarcopenia for the dietary intake of vitamin E (α-tocopherol, 0.14 (CI 0.04-0.49), β-tocopherol (0.24, CI 0.07-0.78), γ-tocopherol (0.28, CI 0.09-0.87), and fats (fat 0.27, CI 0.08-0.96; monounsaturated fatty acids, 0.22, CI 0.07-0.72, polyunsaturated fatty acids, 0.28, CI 0.09-0.89) at the highest quantile were significantly lower compared with those at the lowest quantile. Therefore, higher dietary intakes of vitamin E and fats would be associated with a lower prevalence of sarcopenia.

摘要

饮食习惯是维持肌肉健康(尤其是肌肉减少症)的一个重要可调节因素。本研究旨在探讨社区居住的日本人群中饮食摄入与肌肉减少症患病率之间的关系。本横断面研究使用来自关节炎/骨质疏松症对残疾的研究(ROAD)第五次调查的数据进行,纳入了 1345 名年龄≥60 岁的参与者(男性 437 名,女性 908 名)。肌肉减少症根据 2014 年亚洲肌肉减少症工作组的定义确定,饮食摄入通过简短型自我管理饮食史问卷进行评估。总体而言,77 名(5.7%)参与者被确定为患有肌肉减少症,其中男性占 5.0%,女性占 6.1%。多因素逻辑回归分析显示,维生素 E(α-生育酚 0.14(95%CI 0.04-0.49)、β-生育酚 0.24(95%CI 0.07-0.78)、γ-生育酚 0.28(95%CI 0.09-0.87)和脂肪(脂肪 0.27(95%CI 0.08-0.96);单不饱和脂肪酸 0.22(95%CI 0.07-0.72),多不饱和脂肪酸 0.28(95%CI 0.09-0.89))最高四分位数组的肌肉减少症患病比值比显著低于最低四分位数组。因此,较高的维生素 E 和脂肪饮食摄入量与较低的肌肉减少症患病率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc79/8161000/cc86fbb2dc30/nutrients-13-01730-g001.jpg

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