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自动化尿液分析仪中的非典型细胞参数:它有未来吗?

Atypical cells parameter in an automated urine analyzer: Does it have a future?

机构信息

Biochemistry Laboratory, Kepez Public Hospital, Antalya, Turkey.

出版信息

Anal Biochem. 2020 Jul 1;600:113763. doi: 10.1016/j.ab.2020.113763. Epub 2020 May 4.

Abstract

Sysmex UN-Series automated urine analyzer has recently introduced "atypical cells" parameter. These cells are supposed to be epithelial cells with features of suspicion for a neoplastic proliferation. Atypical cells parameter in urinalysis should be considered to be as useful as the blast parameter in hematology. However, it has many disadvantages compared to its counterpart. I suggest it should be used as a caution flag rather than a quantitative value to appear in the patient result page. A decision limit must be defined; perhaps the color parameter should be matched to define patients with both hematuria and atypical cells.

摘要

希森美康 UN 系列全自动尿液分析仪最近引入了“非典型细胞”参数。这些细胞被认为是具有疑似肿瘤增殖特征的上皮细胞。尿液分析中的非典型细胞参数应该被认为与血液学中的原始细胞参数一样有用。然而,与后者相比,它有许多缺点。我建议将其用作警告标志,而不是定量值出现在患者结果页面上。必须定义一个决策界限;也许应该匹配颜色参数来定义既有血尿又有非典型细胞的患者。

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