Ihle-Hansen Håkon, Berge Trygve, Tveita Anders, Rønning Else Johanne, Ernø Per Erik, Andersen Elizabeth Lyster, Wang Christian Hjorth, Tveit Arnljot, Myrstad Marius
Tidsskr Nor Laegeforen. 2020 Apr 10;140(7). doi: 10.4045/tidsskr.20.0301. Print 2020 May 5.
The COVID-19 outbreak is presenting the health system with new challenges, and there is a great need for knowledge about symptoms, clinical findings and course of illness in patients admitted to Norwegian hospitals with COVID-19.
In this observational qualitative study, all patients admitted to a Norwegian local hospital (Bærum Hospital) with proven COVID-19 infection were included consecutively from the start of the outbreak. We present here patient characteristics, symptoms, clinical findings, experience of using clinical scoring systems and course of illness based on data in medical records.
In the period 9-31 March 2020, 42 patients, of whom 28 (67 %) were men, were admitted to hospital with COVID-19 infection. The median age was 72.5 years (range 30-95). Fever (79 %), reduced general condition (79 %), dyspnoea (69 %) and cough (67 %) were the most common symptoms. A total of nine patients (21 %) had a critical course of illness with treatment in the Intensive Care Department and/or death during their stay in hospital. Patients with a critical course had a higher average score on National Early Warning Score 2 (NEWS2) on admission (7.6 vs 3.3). Only one of the most severely ill patients scored ≥ 2 on the quick Sepsis-related Organ Failure Assessment (qSOFA) on admission.
Most patients admitted to our hospital with COVID-19 had a fever and respiratory tract symptoms. A high percentage of patients had a critical course of illness. A NEWS2 score of ≥ 5 on admission may be a useful aid in identifying patients at risk of a critical course of illness, while CRB-65 and qSOFA score ≥ 2 proved to be of little usefulness for this purpose in our material.
新型冠状病毒肺炎（COVID-19）疫情给卫生系统带来了新的挑战，对于挪威医院收治的COVID-19患者的症状、临床检查结果及病程的了解存在很大需求。
在这项观察性定性研究中，自疫情开始起连续纳入了挪威一家当地医院（贝鲁姆医院）收治的所有确诊COVID-19感染的患者。我们在此基于病历数据呈现患者特征、症状、临床检查结果、使用临床评分系统的经验及病程。
在2020年3月9日至31日期间，42例患者因COVID-19感染入院，其中28例（67%）为男性。年龄中位数为72.5岁（范围30 - 95岁）。发热（79%）、一般状况下降（79%）、呼吸困难（69%）和咳嗽（67%）是最常见的症状。共有9例患者（21%）病程严重，在住院期间需在重症监护室接受治疗和/或死亡。病程严重的患者入院时国家早期预警评分2（NEWS2）的平均分更高（7.6对3.3）。在入院时，病情最严重的患者中只有1例在快速脓毒症相关器官功能衰竭评估（qSOFA）中得分≥2。
我们医院收治的大多数COVID-19患者有发热和呼吸道症状。很大比例的患者病程严重。入院时NEWS2评分≥5可能有助于识别有病程严重风险的患者，而在我们的研究材料中，CRB-65和qSOFA评分≥2在这方面几乎没有用处。
