Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Curr Neuropharmacol. 2021;19(1):92-96. doi: 10.2174/1570159X18666200507085335.
The pandemic novel coronavirus disease (COVID-19) has become a global concern in which the respiratory system is not the only one involved. Previous researches have presented the common clinical manifestations including respiratory symptoms (i.e., fever and cough), fatigue and myalgia. However, there is limited evidence for neurological and psychological influences of SARS-CoV-2. In this review, we discuss the common neurological manifestations of COVID-19 including acute cerebrovascular disease (i.e., cerebral hemorrhage) and muscle ache. Possible viral transmission to the nervous system may occur via circulation, an upper nasal transcribrial route and/or conjunctival route. Moreover, we cannot ignore the psychological influence on the public, medical staff and confirmed patients. Dealing with public psychological barriers and performing psychological crisis intervention are an important part of public health interventions.
新型冠状病毒肺炎(COVID-19)疫情已成为全球关注的焦点,呼吸系统并非唯一受累系统。既往研究已经提出了常见的临床症状,包括呼吸系统症状(如发热和咳嗽)、乏力和肌痛。然而,关于 SARS-CoV-2 对神经系统和心理的影响证据有限。在本综述中,我们讨论了 COVID-19 的常见神经系统表现,包括急性脑血管病(如脑出血)和肌肉疼痛。病毒可能通过循环、经鼻颅前窝途径和/或结膜途径传播到神经系统。此外,我们不能忽视对公众、医务人员和确诊患者的心理影响。应对公众的心理障碍并进行心理危机干预是公共卫生干预的重要组成部分。