Department of Anesthesiology and Intensive Therapy, Semmelweis University, Ulloi ut 78/B, Budapest, 1082, Hungary.
Department of Pulmonology, Semmelweis University, Tomo utca 25-29, Budapest, 1083, Hungary.
BMC Pulm Med. 2020 May 7;20(1):130. doi: 10.1186/s12890-020-1171-5.
Home mechanical ventilation is a reliable treatment for patients suffering from chronic respiratory failure, improving survival and quality of life. Prevalence has been increasing worldwide as a result of evolving technical possibilities, telemedicine and improving national guidelines. Projects to establish a national guideline and registry for patients treated with home mechanical ventilation are currently under way in Hungary and our aim was to validate a quality of life questionnaire suited for evaluation and follow up in this specific patient group. The Severe Respiratory Insufficiency Questionnaire (SRI) is a quality of life tool designed to evaluate patients receiving home mechanical ventilation and has been validated both in patient groups receiving invasive and noninvasive ventilation.
The Hungarian version of the SRI was created using the translation-backtranslation method, which was then tested for validity, viability and reliability in a cohort involving patients from three centers, receiving long-term home mechanical ventilation for chronic respiratory failure through an invasive or noninvasive interface. Patient data was collected (demographic data, lung function test, arterial blood gas, ventilation settings) and quality of life was measured with the previously validated SF-36 and newly created Hungarian SRI Questionnaires at two time points.
One hundred four patients receiving home mechanical ventilation were enrolled. The time to complete the SRI Questionnaire was 8.6 (±3.1) minutes, 69.2% questionnaires were self-administered. Exploratory factor analysis explained 73.8% of the variance of the questionnaire, but resulted in 13 scales. We found correlations between the SRI subscale scores to corresponding scales of the previously validated general quality of life survey SF-36. The Cronbach alpha coefficient was 0.928 for the Summary Scale of the SRI Questionnaire, proving high internal consistency. Reproducibility was high for most scales, resulting in a high overall correlation for the summary score (0.877, p < 0.001).
The Hungarian version of the SRI Questionnaire is a viable, valid, reliable and reproduceable quality of life tool applicable for patients treated with home mechanical ventilation.
家庭机械通气是治疗慢性呼吸衰竭患者的可靠方法，可提高生存率和生活质量。由于技术可能性的不断发展、远程医疗和国家指南的不断完善，全球范围内的患病率一直在上升。目前，匈牙利正在开展建立家庭机械通气治疗患者国家指南和登记处的项目，我们的目的是验证适合评估和随访这一特定患者群体的生活质量问卷。严重呼吸衰竭问卷（SRI）是一种用于评估接受家庭机械通气治疗的患者的生活质量工具，已在接受有创和无创通气的患者群体中得到验证。
使用翻译-回译法创建 SRI 的匈牙利语版本，然后在涉及来自三个中心的患者的队列中对其进行有效性、可行性和可靠性测试，这些患者因慢性呼吸衰竭通过有创或无创接口接受长期家庭机械通气。收集患者数据（人口统计学数据、肺功能测试、动脉血气、通气设置），并使用先前验证的 SF-36 和新创建的匈牙利 SRI 问卷在两个时间点测量生活质量。
共纳入 104 例接受家庭机械通气的患者。完成 SRI 问卷的时间为 8.6（±3.1）分钟，69.2%的问卷为自我管理。探索性因素分析解释了问卷方差的 73.8%，但产生了 13 个量表。我们发现 SRI 子量表评分与先前验证的一般生活质量调查 SF-36 的相应量表之间存在相关性。SRI 问卷综合量表的克朗巴赫 α 系数为 0.928，证明了内部一致性高。大多数量表的可重复性较高，导致综合评分的总体相关性较高（0.877，p<0.001）。
匈牙利语版 SRI 问卷是一种可行、有效、可靠且可重复的生活质量工具，适用于接受家庭机械通气治疗的患者。
