SARS-CoV-2 receptor ACE2 expression in the human heart: cause of a post-pandemic wave of heart failure?
作者信息
Thum Thomas
机构信息
Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Hannover, Germany.
REBIRTH Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany.
出版信息
Eur Heart J. 2020 May 14;41(19):1807-1809. doi: 10.1093/eurheartj/ehaa410.
Abstract
摘要
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SARS-CoV-2 receptor ACE2 expression in the human heart: cause of a post-pandemic wave of heart failure?严重急性呼吸综合征冠状病毒2（SARS-CoV-2）受体血管紧张素转换酶2（ACE2）在人心脏中的表达：大流行后心力衰竭浪潮的原因？
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Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts.人心脏中假定的新型冠状病毒受体血管紧张素转换酶2的细胞类型特异性表达。
Eur Heart J. 2020 May 14;41(19):1804-1806. doi: 10.1093/eurheartj/ehaa311.
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Cardiac and arrhythmic complications in patients with COVID-19.COVID-19 患者的心脏和心律失常并发症。
J Cardiovasc Electrophysiol. 2020 May;31(5):1003-1008. doi: 10.1111/jce.14479. Epub 2020 Apr 13.
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Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection.一名感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的患者出现急性心肌炎，表现为反向Tako-Tsubo综合征。
Eur Heart J. 2020 May 14;41(19):1861-1862. doi: 10.1093/eurheartj/ehaa286.
4
The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2.人类心脏中的 ACE2 表达表明了 SARS-CoV-2 感染患者心脏损伤的新潜在机制。
Cardiovasc Res. 2020 May 1;116(6):1097-1100. doi: 10.1093/cvr/cvaa078.
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SARS-CoV2: should inhibitors of the renin-angiotensin system be withdrawn in patients with COVID-19?严重急性呼吸综合征冠状病毒2：2019冠状病毒病患者是否应停用肾素-血管紧张素系统抑制剂？
Eur Heart J. 2020 May 14;41(19):1801-1803. doi: 10.1093/eurheartj/ehaa235.
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Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on ST-Segment-Elevation Myocardial Infarction Care in Hong Kong, China.2019年冠状病毒病（COVID-19）疫情对中国香港ST段抬高型心肌梗死治疗的影响
Circ Cardiovasc Qual Outcomes. 2020 Apr;13(4):e006631. doi: 10.1161/CIRCOUTCOMES.120.006631. Epub 2020 Mar 17.
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）进入细胞依赖于 ACE2 和 TMPRSS2，可被一种临床验证的蛋白酶抑制剂所阻断。
Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.中国武汉 99 例 2019 年新型冠状病毒肺炎患者的流行病学和临床特征：描述性研究。
Lancet. 2020 Feb 15;395(10223):507-513. doi: 10.1016/S0140-6736(20)30211-7. Epub 2020 Jan 30.
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Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.血管紧张素转换酶抑制和血管紧张素II受体阻滞剂对心脏血管紧张素转换酶2的影响。
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Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.SARS冠状病毒功能性受体ACE2蛋白的组织分布。理解SARS发病机制的第一步。
J Pathol. 2004 Jun;203(2):631-7. doi: 10.1002/path.1570.
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