Young R E, Ramsay L E, Murray T S
Postgrad Med J. 1977 Apr;53(618):212-5. doi: 10.1136/pgmj.53.618.212.
In a retrospective study, based on a biochemical survey of people aged 65 and over in a general practice, subjects taking a barbiturate preparation for indications other than epilepsy had a significantly lower serum calcium concentration than did those taking nitrazepam or diazepam. Ordinary doses of barbiturate may adversely affect vitamin D metabolism in the elderly.
在一项回顾性研究中，基于对一家普通诊所65岁及以上人群的生化调查，因非癫痫适应症而服用巴比妥酸盐制剂的受试者血清钙浓度显著低于服用硝西泮或地西泮的受试者。普通剂量的巴比妥酸盐可能会对老年人的维生素D代谢产生不利影响。
