Department of Pharmacology, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj-757086, Odisha, India.
Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj-757086, Odisha, India.
Curr Drug Deliv. 2020;17(7):558-576. doi: 10.2174/1567201817999200508092821.
The scope of nanotechnology has been extended to almost every sphere of our daily life. As a result of this, nanocarriers like Carbon Nanotubes (CNTs) are gaining considerable attention for their use in various therapeutic and diagnostic applications.
The objective of the current article is to review various important features of CNTs that make them as efficient carriers for anticancer drug delivery in cancer therapeutics.
In this review article, different works of literature are reported on various prospective applications of CNTs in the targeting of multiple kinds of cancerous cells of different organs via; the loading of various anticancer agents.
Actually, CNTs are the 3rd allotropic type of the carbon-fullerenes that are a part of the cylindrical tubular architecture. CNTs possess some excellent physicochemical characteristics and unique structural features that provide an effective platform to deliver anticancer drugs to target specific sites for achieving a high level of therapeutic effectiveness even in cancer therapeutics. For better results, CNTs are functionalized and modified with different classes of therapeutically bioactive molecules via; the formation of stable covalent bonding or by the use of supramolecular assemblies based on the noncovalent interaction(s). In recent years, the applications of CNTs for the delivery of various kinds of anticancer drugs and targeting of tumor sites have been reported by various research groups.
CNTs represent an emerging nanocarrier material for the delivery and targeting of numerous anticancer drugs in cancer therapeutics.
纳米技术的应用范围已经扩展到我们日常生活的几乎各个领域。因此，碳纳米管（CNTs）等纳米载体因其在各种治疗和诊断应用中的应用而受到广泛关注。
本文的目的是综述 CNTs 的各种重要特性，这些特性使它们成为癌症治疗中抗癌药物输送的有效载体。
在这篇综述文章中，报道了不同文献中 CNTs 在通过；不同器官的多种癌细胞的靶向方面的各种有前景的应用。负载各种抗癌剂。
实际上，CNTs 是富勒烯的第三种同素异形体，是圆柱形管状结构的一部分。CNTs 具有一些优异的物理化学特性和独特的结构特征，为将抗癌药物递送到特定的目标部位提供了有效的平台，即使在癌症治疗中也能实现高水平的治疗效果。为了获得更好的效果，通过；稳定的共价键形成或使用基于非共价相互作用的超分子组装，用不同类别的治疗生物活性分子对 CNTs 进行功能化和修饰。近年来，不同研究小组已经报道了 CNTs 在递送至各种抗癌药物和肿瘤部位的靶向方面的应用。
CNTs 代表了一种新兴的纳米载体材料，可用于癌症治疗中众多抗癌药物的输送和靶向。
