新型冠状病毒病（COVID-19）相关的重症胰腺炎：一家三口发病病例报告。
Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members.
机构信息
Pancreatitis Centre East, Gastrounit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Pancreatitis Centre East, Gastrounit, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
出版信息
Pancreatology. 2020 Jun;20(4):665-667. doi: 10.1016/j.pan.2020.04.021. Epub 2020 May 5.
BACKGROUND/OBJECTIVES: Abdominal pain is one of the known symptoms associated with coronavirus disease 2019. Little is known about the development of acute pancreatitis as a complication of severe acute respiratory syndrome coronavirus 2 infection. This case report describes the presentation of acute pancreatitis in two of three family members with severe COVID-19 infection.
METHODS
Data were collected from three family members admitted with COVID-19 to the intensive care unit in March 2020. This study was reviewed and approved by the local data and ethics committee (31-1521-253).
RESULTS
Two of the three family members were diagnosed with acute pancreatitis associated with SARS-CoV-2. Other causes of acute pancreatitis were excluded for both patients (including alcohol, biliary obstruction/gall stones, drugs, trauma, hypertriglyceridemia, hypercalcemia, and hypotension).
CONCLUSIONS
These cases highlight acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain.
背景/目的：腹痛是与 2019 年冠状病毒病相关的已知症状之一。关于严重急性呼吸综合征冠状病毒 2 感染作为急性胰腺炎并发症的发展，知之甚少。本病例报告描述了 3 名严重 COVID-19 感染患者中 2 名家庭成员发生急性胰腺炎的表现。
方法
从 2020 年 3 月因 COVID-19 入住重症监护病房的 3 名家庭成员中收集数据。本研究经当地数据和伦理委员会（31-1521-253）审查和批准。
结果
3 名家庭成员中有 2 名被诊断为 SARS-CoV-2 相关的急性胰腺炎。排除了这两名患者的其他急性胰腺炎病因（包括酒精、胆道梗阻/胆石症、药物、创伤、高甘油三酯血症、高钙血症和低血压）。
结论
这些病例强调了急性胰腺炎是 COVID-19 的一种并发症，并强调了在 COVID-19 患者和腹痛患者中测量胰腺特异性血浆淀粉酶的重要性。
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