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新型冠状病毒肺炎(COVID-19)与急性坏死性胰腺炎(ANP)相关。

Coronavirus disease-19 (COVID-19) associated with acute necrotising pancreatitis (ANP).

作者信息

Kumaran Naren K, Karmakar Biraj K, Taylor Ormond M

机构信息

Department of General Surgery, Kettering General Hospital NHS Foundation Trust, Kettering, UK

Department of General Surgery, Kettering General Hospital NHS Foundation Trust, Kettering, UK.

出版信息

BMJ Case Rep. 2020 Sep 7;13(9):e237903. doi: 10.1136/bcr-2020-237903.

Abstract

Coronavirus is a severe infectious disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has led to increased mortality worldwide. Multiple reports have been published citing that gastrointestinal symptoms are common in patients with COVID-19 infection. It has also been found that the ACE2 receptor of SARS-CoV-2 is expressed more in the pancreas than the lungs. Despite this, little attention has been paid to the extent and details of pancreatic injury caused by COVID-19. Lack of awareness regarding the COVID-19 status of patients presenting with pancreatitis may expose healthcare workers to SARS-CoV-2 while performing interventions to manage complications of pancreatitis such as necrosis. We report a case of COVID-19-induced acute necrotising pancreatitis in the absence of any known risk factors.

摘要

冠状病毒病是由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的一种严重传染病(COVID-19),已导致全球死亡率上升。多项报告指出,胃肠道症状在COVID-19感染患者中很常见。还发现SARS-CoV-2的血管紧张素转换酶2(ACE2)受体在胰腺中的表达高于肺部。尽管如此,COVID-19引起的胰腺损伤的程度和细节却很少受到关注。对胰腺炎患者的COVID-19状况缺乏认识,可能会使医护人员在进行干预以处理胰腺炎并发症(如坏死)时接触到SARS-CoV-2。我们报告一例在无任何已知危险因素情况下由COVID-19引起的急性坏死性胰腺炎病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6aa/7477985/a64731ba7c78/bcr-2020-237903f01.jpg

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