Kumaran Naren K, Karmakar Biraj K, Taylor Ormond M
Department of General Surgery, Kettering General Hospital NHS Foundation Trust, Kettering, UK
Department of General Surgery, Kettering General Hospital NHS Foundation Trust, Kettering, UK.
BMJ Case Rep. 2020 Sep 7;13(9):e237903. doi: 10.1136/bcr-2020-237903.
Coronavirus is a severe infectious disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has led to increased mortality worldwide. Multiple reports have been published citing that gastrointestinal symptoms are common in patients with COVID-19 infection. It has also been found that the ACE2 receptor of SARS-CoV-2 is expressed more in the pancreas than the lungs. Despite this, little attention has been paid to the extent and details of pancreatic injury caused by COVID-19. Lack of awareness regarding the COVID-19 status of patients presenting with pancreatitis may expose healthcare workers to SARS-CoV-2 while performing interventions to manage complications of pancreatitis such as necrosis. We report a case of COVID-19-induced acute necrotising pancreatitis in the absence of any known risk factors.
冠状病毒病是由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的一种严重传染病(COVID-19),已导致全球死亡率上升。多项报告指出,胃肠道症状在COVID-19感染患者中很常见。还发现SARS-CoV-2的血管紧张素转换酶2(ACE2)受体在胰腺中的表达高于肺部。尽管如此,COVID-19引起的胰腺损伤的程度和细节却很少受到关注。对胰腺炎患者的COVID-19状况缺乏认识,可能会使医护人员在进行干预以处理胰腺炎并发症(如坏死)时接触到SARS-CoV-2。我们报告一例在无任何已知危险因素情况下由COVID-19引起的急性坏死性胰腺炎病例。