Zhao Yanyan, Li Hongyu, Chai Ziyin, Shi Wen, Li Xiaohua, Ma Huimin
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Chem Commun (Camb). 2020 Jun 14;56(47):6344-6347. doi: 10.1039/d0cc00233j. Epub 2020 May 11.
The hydroxyl radical (˙OH) in the endoplasmic reticulum has not been studied thoroughly due to the lack of proper methods. Here, an endoplasmic reticulum-targeting fluorescent probe for detecting ˙OH is reported. With this probe, the action of ˙OH in the endoplasmic reticulum has been imaged in living cells.
由于缺乏合适的方法，内质网中的羟基自由基（˙OH）尚未得到充分研究。在此，报道了一种用于检测˙OH的内质网靶向荧光探针。利用该探针，已在活细胞中对内质网中˙OH的作用进行了成像。
