人类树突是否不同？
Are Human Dendrites Different?
机构信息
Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK; Department of Neuroscience, Physiology, and Pharmacology, University College London, Gower Street, London, WC1E 6BT, UK.
Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK; Department of Neuroscience, Physiology, and Pharmacology, University College London, Gower Street, London, WC1E 6BT, UK.
出版信息
Trends Cogn Sci. 2020 Jun;24(6):411-412. doi: 10.1016/j.tics.2020.03.002. Epub 2020 Mar 30.
Abstract
The first patch-clamp recordings from the dendrites of human neocortical neurons have recently been reported by Beaulieu-Laroche et al. and Gidon et al. These studies have shown that human dendrites are electrically excitable, exhibiting backpropagating action potentials and fast dendritic calcium spikes. This new frontier highlights the potential for interspecies differences in the biophysics of dendritic computation.
摘要
最近，Beaulieu-Laroche 等人和 Gidon 等人报道了人类新皮层神经元树突的首次膜片钳记录。这些研究表明，人类树突具有电兴奋性，可产生逆行动作电位和快速树突钙峰。这一新的前沿领域强调了树突计算的生物物理学在种间可能存在差异。
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