Kim Su Il, Lechien Jerome R, Ayad Tareck, Jia Huan, Khoddami Seyyedeh Maryam, Enver Necati, Raghunandhan Sampath Kumar, Hamdan Abdul Latif, Eun Young-Gyu
Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies, Paris, France.
Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2020 Aug;13(3):299-307. doi: 10.21053/ceo.2019.01669. Epub 2020 May 12.
This study was conducted to investigate the current practices of Asian otolaryngologists for laryngopharyngeal reflux (LPR).
An online survey about LPR was sent to 2,000 members of Asian otolaryngological societies, and a subgroup analysis was performed between Western and Eastern Asian otolaryngologists. The survey was conducted by the Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies.
Among approximately 1,600 Asian otolaryngologists, 146 completed the survey (62 from Western Asian countries, 84 from Eastern Asian countries). A substantial majority (73.3%) of the otolaryngologists considered LPR and gastroesophageal reflux disease to be different diseases. The symptoms thought to be closely related to LPR were coughing after lying down, throat clearing, and globus sensation. The findings thought to be closely related to LPR were posterior commissure granulations and hypertrophy, arytenoids, and laryngeal erythema. The respondents indicated that they mostly diagnosed LPR (70%) after an empirical therapeutic trial of proton pump inhibitors (PPIs). Although multichannel intraluminal impedance-pH (MII-pH) monitoring is a useful tool for diagnosing nonacid or mixed LPR, 78% of Asian otolaryngologists never or very rarely used MII-pH. Eastern Asian otolaryngologists more frequently used once-daily PPIs (64.3% vs. 45.2%, P=0.021), whereas Western Asian otolaryngologists preferred to use twice-daily PPIs (58.1% vs. 39.3%, P=0.025). The poor dietary habits of patients were considered to be the main reason for therapeutic failure by Asian otolaryngologists (53.8%). Only 48.6% of Asian otolaryngologists considered themselves to be adequately knowledgeable and skilled regarding LPR.
Significant differences exist between Western and Eastern Asian otolaryngologists in the diagnosis and treatment of LPR. Future consensus statements are needed to establish diagnostic criteria and therapeutic regimens.
本研究旨在调查亚洲耳鼻喉科医生对喉咽反流(LPR)的当前诊疗实践。
一项关于LPR的在线调查被发送给2000名亚洲耳鼻喉科协会成员,并对西亚和东亚耳鼻喉科医生进行了亚组分析。该调查由国际耳鼻喉科协会青年耳鼻喉科医生喉咽反流研究小组开展。
在约1600名亚洲耳鼻喉科医生中,146人完成了调查(62人来自西亚国家,84人来自东亚国家)。绝大多数(73.3%)耳鼻喉科医生认为LPR和胃食管反流病是不同的疾病。被认为与LPR密切相关的症状是躺下后咳嗽、清嗓和咽部异物感。被认为与LPR密切相关的检查结果是后联合颗粒和肥大、杓状软骨以及喉部红斑。受访者表示,他们大多(70%)在质子泵抑制剂(PPI)经验性治疗试验后诊断LPR。尽管多通道腔内阻抗-pH(MII-pH)监测是诊断非酸性或混合性LPR的有用工具,但78%的亚洲耳鼻喉科医生从未或很少使用MII-pH。东亚耳鼻喉科医生更频繁地使用每日一次的PPI(64.3%对45.2%,P=0.021),而西亚耳鼻喉科医生更喜欢使用每日两次的PPI(58.1%对39.3%,P=0.025)。亚洲耳鼻喉科医生认为患者不良的饮食习惯是治疗失败的主要原因(53.8%)。只有48.6%的亚洲耳鼻喉科医生认为自己对LPR有足够的知识和技能。
西亚和东亚耳鼻喉科医生在LPR的诊断和治疗方面存在显著差异。需要未来的共识声明来确立诊断标准和治疗方案。