Zhang Yingyi, Cong Hongliang, Man Chen, Su Yu, Sun Hongxia, Yang Hua, Guo Zhigang
Department of Cardiology, Tianjin Chest Hospital, Tianjin 300222, China.
Department of Health Education, Tianjin Hedong District Center for Disease Control and Prevention, Tianjin 300011, China.
Ann Transl Med. 2020 Apr;8(7):444. doi: 10.21037/atm.2020.03.139.
Cardiovascular disease (CVD) is a harmful disease that poses a serious threat to human life. By effectively controlling its risk factors, the occurrence and development of CVD can be reduced, and people's health status and quality of life can be improved.
A total of 36,215 participants were collected from participants of the Early Screening and Comprehensive Intervention Program for High Risk Population of Cardiovascular Disease in Tianjin on July 31, 2017. We analyzed the relationship between CVD risk and personal information, personal and family medical history, biochemical index, and physical fitness index using Pearson's chi-squared test with and without Yates's correction for continuity, and Fisher's exact test. CVD risk-related factors were examined through logistic regression and decision tree analysis.
A personal history of hypertension and apoplexy had a contingency coefficient with CVD risk of more than 0.3. A higher risk of CVD was also found to be associated with biochemical markers of cholesterol, low-density lipoprotein cholesterol, and blood sugar. Logistic regression analysis revealed 12 indicators to be influencing factors of CVD, including age, systolic blood pressure (SBP), diastolic blood pressure (DBP), and the number of people aged >90 in the family. Hypertension, SBP, BMI, cholesterol, and blood glucose were associated with five or more other indicators.
The prevalence of CVD risk factors in Tianjin residents is relatively high. Family disease history and individual physical fitness indicators need to be taken into account during CVD screening and intervention, to reduce the risk of CVD.
心血管疾病（CVD）是一种对人类生命构成严重威胁的有害疾病。通过有效控制其危险因素，可以降低心血管疾病的发生和发展，并改善人们的健康状况和生活质量。
2017年7月31日，从天津市心血管疾病高危人群早期筛查与综合干预项目的参与者中总共收集了36215名参与者。我们使用带和不带Yates连续性校正的Pearson卡方检验以及Fisher精确检验，分析了心血管疾病风险与个人信息、个人和家族病史、生化指标以及体能指标之间的关系。通过逻辑回归和决策树分析检查心血管疾病风险相关因素。
高血压和中风的个人病史与心血管疾病风险的列联系数超过0.3。还发现心血管疾病的较高风险与胆固醇、低密度脂蛋白胆固醇和血糖的生化标志物有关。逻辑回归分析显示12个指标是心血管疾病的影响因素，包括年龄、收缩压（SBP）、舒张压（DBP）以及家庭中90岁以上的人数。高血压、收缩压、体重指数、胆固醇和血糖与其他五个或更多指标相关。
天津居民心血管疾病危险因素的患病率相对较高。在心血管疾病筛查和干预过程中，需要考虑家族病史和个体体能指标，以降低心血管疾病风险。
