Facultad de Ciencias Biológicas, Universidad Autónoma de Coahuila, Carretera Torreón-Matamoros Km 7.5, Torreón Coahuila 27104, Mexico.
Tecnológico de Monterrey, School of Engineering and Sciences, Eugenio Garza Sada 2501, Col. Tecnológico, Monterrey Nuevo León 64849, Mexico.
Int J Mol Sci. 2020 May 8;21(9):3322. doi: 10.3390/ijms21093322.
Legumes are affected by biotic factors such as insects, molds, bacteria, and viruses. These plants can produce many different molecules in response to the attack of phytopathogens. Protease inhibitors (PIs) are proteins produced by legumes that inhibit the protease activity of phytopathogens. PIs are known to reduce nutrient availability, which diminishes pathogen growth and can lead to the death of the pathogen. PIs are classified according to the specificity of the mechanistic activity of the proteolytic enzymes, with serine and cysteine protease inhibitors being studied the most. Previous investigations have reported the efficacy of these highly stable proteins against diverse biotic factors and the concomitant protective effects in crops, representing a possible replacement of toxic agrochemicals that harm the environment.
豆类受到昆虫、霉菌、细菌和病毒等生物因素的影响。这些植物可以产生许多不同的分子来应对植物病原体的攻击。蛋白酶抑制剂 (PI) 是豆类产生的蛋白质，可抑制植物病原体的蛋白酶活性。已知 PI 会降低营养物质的可用性，从而减少病原体的生长，并可能导致病原体死亡。PI 根据其对蛋白水解酶的机制活性的特异性进行分类，其中研究最多的是丝氨酸和半胱氨酸蛋白酶抑制剂。以前的研究报告了这些高度稳定的蛋白质对多种生物因素的功效以及在作物中的保护作用，这代表了一种可能替代对环境有害的有毒农用化学品的方法。
