尼日利亚罐装沙丁鱼中的多氯联苯及其健康风险评估。
Polychlorinated biphenyls in canned sardines in Nigeria and health risk assessment.
机构信息
Department of Chemical Sciences, University of Africa , Toru-Orua, Nigeria.
Department of Chemistry, Federal University , Otuoke, Nigeria.
出版信息
Food Addit Contam Part B Surveill. 2020 Sep;13(3):200-206. doi: 10.1080/19393210.2020.1762758. Epub 2020 May 13.
The concentrations and potential human health risks through dietary ingestion of PCBs in canned sardines collected from the Nigerian market were determined. The results shows that the total PCBs concentrations varied from <LOD to 668 ng g. The composition of PCBs in the canned sardines followed the order: Penta-PCBs > Hexa-PCBs > Tetra-PCBs > Di-PCB > Deca-PCB > Tri-PCBs > Hepta-PCBs > Octa-PCB. The estimated daily intake for total PCBs ranged from <LOD to 926 ng kg bw day and < LOD to 232 ng kg bw day for child and adult exposures respectively. The TEQs values of the dl-PCBs indicated that these canned sardines are unsafe for consumption. The hazard index and total cancer risk values in 53% of the canned sardines were greater than 1 and 1 × 10 respectively indicating that there are adverse non-carcinogenic and carcinogenic risks associated with human consumption of these canned sardines.
测定了从尼日利亚市场采集的罐装沙丁鱼中通过饮食摄入 PCB 的浓度和潜在的人类健康风险。结果表明，总 PCB 浓度从低于检测限到 668ng/g 不等。罐装沙丁鱼中 PCB 的组成顺序为：五氯联苯>六氯联苯>四氯联苯>二氯联苯>十氯联苯>三氯联苯>七氯联苯>八氯联苯。总 PCB 的估计日摄入量范围为低于检测限到 926ng/kgbw 天和低于检测限到 232ng/kgbw 天，分别适用于儿童和成人的暴露。dl-PCBs 的毒性当量值表明，这些罐装沙丁鱼不宜食用。在 53%的罐装沙丁鱼中，危害指数和总癌症风险值大于 1 和 1×10，这表明人类食用这些罐装沙丁鱼存在不良的非致癌和致癌风险。
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