Ranade Anagha Vishwas, Shirolkar Amey, Pawar Sharad Daulatrao
Research Officer (Ayu), Department of Pharmacology, Regional Ayurved Institute for Fundamental Research, Pune, Maharashtra, India.
Department of Biochemistry, National Centre for Cell Sciences, Pune, Maharashtra, India.
Ayu. 2019 Apr-Jun;40(2):75-78. doi: 10.4103/ayu.AYU_210_18. Epub 2020 Mar 20.
With the increasing resurgence of Ayurvedic medicine in recent years, a lot of focus is laid on pharmacokinetics of herbs in arresting disease pathology. Ayurveda has enlisted some fundamentals in relation to drug pharmacokinetics, namely (perception), (potency), (postdigestive effect), (properties), and (special effect). In recent years, research has emphasized the role of gut microbiota in human health and metabolic processes. A thorough review was done to understand the role of microbiota in drug metabolism if any. The holistic mechanism of gut microbiota coincides to some extent, with the doctrines of Ayurveda in the context of pharmacodynamics and pharmacokinetics. This discussion is a thought put forth with an aim to elucidate the concept of gut microbiota functions.
近年来，随着阿育吠陀医学的日益复兴，人们将大量注意力集中在草药的药代动力学对疾病病理的抑制作用上。阿育吠陀医学已经列出了一些与药物药代动力学相关的基本要素，即（感知）、（药力）、（消化后效应）、（特性）和（特殊效应）。近年来，研究强调了肠道微生物群在人类健康和代谢过程中的作用。我们进行了全面的综述，以了解微生物群在药物代谢中（若有）的作用。肠道微生物群的整体机制在一定程度上与阿育吠陀医学在药效学和药代动力学方面的学说相契合。本讨论旨在阐明肠道微生物群功能的概念。
