Ashour Amr, Obeidat Khaldun, Azrieh Bahjat, Alsaud Arwa, Yassin Mohamed
Department of Medical Education, Hamad Medical Corporation, Doha, Qatar.
Case Rep Neurol. 2020 Apr 28;12(1):136-139. doi: 10.1159/000506192. eCollection 2020 Jan-Apr.
Varicella zoster is a secondary infection caused by the virus of chickenpox, after becoming latent in neurons of dorsal root ganglia or trigeminal ganglia. Varicella zoster virus (VZV) can be reactivated years later to produce shingles (zoster), generally in immunocompromised adults to produce neurological deficits and rash. Meningeal involvement of VZV is also reported and can be diagnosed. Herein, we report a 39-year-old immunocompetent male adult with a rare manifestation caused by VZV. The report is an association between facial nerve palsy and a polymerase chain reaction-confirmed VZV meningitis, even without the dermal typical rash. The patient eventually recovered after receiving acyclovir intravenously.
水痘带状疱疹是由水痘病毒引起的继发性感染，该病毒在背根神经节或三叉神经节的神经元中潜伏后发病。水痘带状疱疹病毒（VZV）可在数年之后重新激活，引发带状疱疹，通常发生在免疫功能低下的成年人中，导致神经功能缺损和皮疹。也有关于VZV累及脑膜的报道，且能够作出诊断。在此，我们报告一名39岁免疫功能正常的男性成年人，出现了由VZV引起的罕见表现。本报告是关于面神经麻痹与聚合酶链反应确诊的VZV脑膜炎之间的关联，即便没有典型的皮肤皮疹。该患者在接受静脉注射阿昔洛韦后最终康复。
