Vazquez Oscar A, Markowitz Moses I, Becker Hilton
Surgery, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, USA.
Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, USA.
Cureus. 2020 Apr 9;12(4):e7598. doi: 10.7759/cureus.7598.
Background It is generally believed that trauma to fat grafts is detrimental and affects the survival of the graft. In addition, it has been shown that smaller fat particle size corresponds to better survival; however, smaller cannula openings correspond to slower and more difficult fat graft harvesting. Objectives This study documents the relationship between cannula size, harvested fat cell size, and injection needle size. A means of reducing fat particle size following aspiration with larger diameter cannulas is also discussed. Methods Fat was harvested from five patients undergoing elective liposuction. Each fat sample was placed in a syringe and injected through progressively smaller needles until obstruction under low pressure was obtained. The minimal needle size was documented for each sample. Results Fat harvested with a liposuction cannula results in different size fat particles ranging up to the size of the cannula. Particles obtained from 3- and 4-mm cannulas can be injected without obstruction through a 16-gauge needle. Particles obtained from a 2-mm cannula can be injected without obstruction through an 18-gauge needle. Particles obtained from a 1-mm cannula can be injected without obstruction through a 20-gauge needle. Particles obtained from a 1-mm cannula could not be injected without obstruction through a 22-gauge needle. Conclusions There is a relationship between cannula opening size and the resultant fat graft size. Fat particles are somewhat compressible but should not be forced through needles or cannulas that are too narrow. It may be beneficial to harvest fat with larger cannulas and cut the particles to smaller sizes for injection.
一般认为，脂肪移植受到的创伤是有害的，会影响移植脂肪的存活。此外，研究表明，脂肪颗粒尺寸越小，存活率越高；然而，插管开口越小，脂肪移植采集速度越慢且难度越大。目的：本研究记录了插管尺寸、采集的脂肪细胞大小和注射针尺寸之间的关系。还讨论了使用较大直径插管抽吸后减小脂肪颗粒尺寸的方法。方法：从5名接受择期抽脂术的患者身上采集脂肪。将每个脂肪样本置于注射器中，并通过逐渐变小的针头进行注射，直到在低压下出现阻塞。记录每个样本的最小针头尺寸。结果：用抽脂插管采集的脂肪会产生大小不一的脂肪颗粒，最大可达插管尺寸。通过16号针头可无阻碍地注射从3毫米和4毫米插管采集的颗粒。通过18号针头可无阻碍地注射从2毫米插管采集的颗粒。通过20号针头可无阻碍地注射从1毫米插管采集的颗粒。通过22号针头无法无阻碍地注射从1毫米插管采集的颗粒。结论：插管开口尺寸与最终的脂肪移植尺寸之间存在关联。脂肪颗粒在一定程度上可压缩，但不应强行通过过窄的针头或插管。使用较大插管采集脂肪并将颗粒切割成较小尺寸进行注射可能是有益的。
