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强力霉素,是抗生素还是抗炎药?皮肤科最常见的用途。

Doxycycline, an Antibiotic or an Anti-Inflammatory Agent? The Most Common Uses in Dermatology.

作者信息

Navarro-Triviño F J, Pérez-López I, Ruiz-Villaverde R

机构信息

Unidad de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario San Cecilio, Granada, España.

Unidad de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario San Cecilio, Granada, España.

出版信息

Actas Dermosifiliogr (Engl Ed). 2020 Sep;111(7):561-566. doi: 10.1016/j.ad.2019.12.006. Epub 2020 May 13.

DOI:10.1016/j.ad.2019.12.006
PMID:32401726
Abstract

Doxycycline is a synthetic tetracycline that was approved in 1967. This wide-spectrum antibiotic has been shown to also have useful anti-inflammatory properties that make it suitable for the treatment of a number of noninfectious conditions. Tetracyclines are probably the most commonly prescribed antibiotics in dermatology, where they are usually used at doses lower than those effective against infections. They also have an excellent efficacy and safety profile. Because of doxycycline's ability to inhibit the molecular pathways associated with certain processes, this antibiotic can be used to treat hair follicle diseases, granulomatous diseases, and vascular proliferation, among other conditions. The main properties of doxycycline and its many applications in dermatology make this drug one that specialists should become familiar with.

摘要

强力霉素是一种于1967年获批的合成四环素。这种广谱抗生素已被证明还具有有益的抗炎特性,使其适用于治疗多种非感染性疾病。四环素可能是皮肤科最常用的抗生素,在皮肤科通常使用的剂量低于对感染有效的剂量。它们还具有出色的疗效和安全性。由于强力霉素能够抑制与某些过程相关的分子途径,这种抗生素可用于治疗毛囊疾病、肉芽肿性疾病和血管增殖等病症。强力霉素的主要特性及其在皮肤科的众多应用使这种药物成为专科医生应该熟悉的药物。

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