Down Billy, Kulkarni Sagar, Khan Ameer Hamid Ahmed, Barker Benjamin, Tang Ivan
Milton Keynes University Hospital NHS Foundation Trust, Standing Way, Milton Keynes, Buckinghamshire, MK6 5BY, United Kingdom.
Oxford University Clinical Academic Graduate School, Medical Sciences Division, University of Oxford, John Radcliffe Hospital, Headington, Oxfordshire, OX3 9DU, United Kingdom.
Ann Med Surg (Lond). 2020 May 13;55:24-29. doi: 10.1016/j.amsu.2020.05.014. eCollection 2020 Jul.
Coronavirus disease 2019 (COVID-19) is a zoonotic respiratory infection originating from Wuhan, China. Rapidly spreading from Wuhan to all inhabited continents of the world, the World Health Organisation declared COVID-19 a pandemic on March 11, 2019. Infected patients present with fever and cough; radiological features include bilateral infiltrates on chest x-ray and computed tomography scanning. Management is supportive with oxygen supplementation, broad-spectrum antibiotics as well as careful fluid balancing. A number of drugs, both new and old, are currently in clinical trials and being used on an experimental basis in clinical practice. The COVID-19 pandemic is the greatest worldwide public health crisis of a generation, and has led to seismic political, economic and social changes. This review provides an overview of COVID-19 for junior doctors who find themselves on a new frontline of healthcare.
2019冠状病毒病(COVID-19)是一种源自中国武汉的人畜共患呼吸道感染疾病。它迅速从武汉传播到世界所有有人居住的大陆,世界卫生组织于2019年3月11日宣布COVID-19为大流行病。感染患者表现出发热和咳嗽;影像学特征包括胸部X光和计算机断层扫描显示双侧浸润。治疗以补充氧气、使用广谱抗生素以及谨慎平衡液体为主。目前,许多新药和旧药都在进行临床试验,并在临床实践中进行试验性使用。COVID-19大流行是一代人以来全球最严重的公共卫生危机,并引发了巨大的政治、经济和社会变革。本综述为身处医疗保健新前线的初级医生提供了COVID-19的概述。